International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 127

Survey Paper | Medicine Science | Albania | Volume 3 Issue 12, December 2014


Do Patients With Thalassaemia Major Manifest Endocrine Complications? Can We Solve Them?

Manika Kreka [2] | Eleni Nastas [2] | Xhensila Prendushi | Irena Qendro | Bledi Kreka | Vjollca Shpata


Abstract: It is estimated that endocrine abnormalities are present in thalasaemic patients. Despite the early diagnosis and the optimal iron chelation therapy, there are still important in many clinical situations like: delayed sexual maturation and impaired fertility. The aim of the study was to assess the correlation of ferritin level and growth and sexual hormones of organism in inidividuals with thalassaemia. A statistically negative correlation was found between ferritin level at the end of third year of treatment with Deferasirox and testosterone, (r=-0.6 p


Keywords: thalassaemia, iron, deferasirox, delayed puberty, hypogonadism


Edition: Volume 3 Issue 12, December 2014,


Pages: 379 - 381


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How to Cite this Article?

Manika Kreka, Eleni Nastas, Xhensila Prendushi, Irena Qendro, Bledi Kreka, Vjollca Shpata, "Do Patients With Thalassaemia Major Manifest Endocrine Complications? Can We Solve Them?", International Journal of Science and Research (IJSR), Volume 3 Issue 12, December 2014, pp. 379-381, https://www.ijsr.net/get_abstract.php?paper_id=SUB14241

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