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Case Studies | Medicine | India | Volume 10 Issue 1, January 2021

Rapidly Progressive Renal Failure: A Rare Clinical Presentation of Renal Sarcoidosis

Shivali Sandal ^[2] | Surender Kumar ^[6]

Abstract: A 54 -year-old woman presented with history of easy fatiguability for last 3 months, breathlessness for last 2 months and feverish feelings for last 2 weeks. Initial laboratory findings of a raised serum creatinine & BUN which was increased by 1mg/dl in more than 2 weeks indicative of RPRF (Rapidly progressive renal faliure). Along with other investigations including raised serum calcium, raised serum protein (9.5 g/l) and normal serum albumin (4.3 g/l), lead to an initial working diagnosis of multiple myeloma as a cause of RPRF. However, later serum protein electrophoresis found a polyclonal gammopathy and further investigations lead us to think about granulomatous disorders, and ultimately we reach the diagnosis of systemic sarcoidosis. The patient responded well to steroids. Sarcoidosis is a rare cause of RPRF & polyclonal gammopathy is a less well recognised manifestation of sarcoidosis, its presence should make clinicians to think about the diagnosis of sarcoidosis.

Keywords: RPRF, GIN, polyclonal gammopathy

Edition: Volume 10 Issue 1, January 2021,

Pages: 1402 - 1404

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