M. Devika Priyadarshini
Abstract: Depression is a common but serious disorder. It is very hard to diagnose and some people may suffer from treatment-resistant depression. Depression exploits the person mentally and it leads to serious actions if not treated properly. To evade this along with anti-depressant therapy patients were given augmentation treatments. Lately, ketamine is found to be a promising treatment for Treatment-resistant depression but there are possible risks. Studies have been conducted to determine the ketamine effects and it can be concluded from all the studies that ketamine is effective in treating treatment-resistant depression. But the drug has a risk of being abused and there are some serious side effects. So it can be said that ketamine is a double-edged sword that needs thorough and precise research. This is a review article where some of the studies are briefly discussed.
Keywords: Depression, Ketamine, Major Depressive Disorder, Treatment-Resistant Depression