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Dissertation Chapters | Ophthalmology | India | Volume 9 Issue 5, May 2020
Analyse the Efficacy and Safety of Intravitreal Injection of Biosimilar Ranibizumab on Central Macular Thickness and Visual Outcome in Patients of Macular Edema
Ishita M. Daxini | Komal Bagrecha | Pankti S. Shah
Abstract: The biosimilar ranibizumab like its biologic reference drug (Lucentis; Genentech) is a recombinant humanized IgG1 monoclonal antibody designed for intraocular use. Recombinant humanized IgG1 kappa isotype monoclonal antibody fragment, inhibits the biologic activity of human VEGF-A. In this paper, efficacy of single intravitreal injection of biosimilar ranibizumab on central macular thickness and visual outcome in patients of macular oedema with different retinal etiology is presented. Effect of biosimilar intravitreal ranibizumab for DME, pseudo phakic cystoid macular edema and macular edema secondary to RVO was observed over period of 3 months with improvements in visual acuity and CFT without detectable ocular and systemic toxicity.
Keywords: Intravitreal biosimilar ranibizumab, central macular thickness, visual outcome
Edition: Volume 9 Issue 5, May 2020,
Pages: 860 - 862
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Research Paper, Ophthalmology, India, Volume 12 Issue 9, September 2023
Pages: 752 - 756Effects of Intravitreal Injection Bevacizumab in Posterior Segment Vasculopathies - A Clinical Study
Dr. Abhiraj Mane | Dr. V. H. Karambelkar | Dr. Girish Gadre | Dr. Sanvedya Kadam
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Dissertation Chapters, Ophthalmology, India, Volume 10 Issue 12, December 2021
Pages: 952 - 955Study of Variation in Macular Thickness by OCT in Normal Eye
Dr. Neeti R Sheth [2] | Dr. Beena Viramgama