International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Chemistry | India | Volume 3 Issue 10, October 2014


Synthesis, Characterization and Antimicrobial Activity of various Chalcone Derivatives

Aayushi Sharma | D. P. Pathak


Abstract: Chalcone are precursor of the natural occurring flavonoids family. Chalcone consists of two aromatic rings linked by three carbon carbonyl system. The chemistry and biological activities of Chalcone has motivate to synthesis Chalcone as a potential compound for antimicrobial activity. In the present work, a series of Chalcone derivatives were synthesized by Claisen-Schmidt Condensation reaction in which various substituted benzaldehyde and acetoaryl were condensed in the presence of aqueous alcoholic alkali solution. The structures of these compounds were confirmed on the basis of the spectral data. The compounds were screened for their antibacterial activity against B. subtilius, S. aureus, E. coli, P. aureoginosa and antifungal activity against A. niger. The results indicate that synthesized compounds have appreciable antibacterial and antifungal activity.


Keywords: Chalcone, acetoaryl, antimicrobial activity, parallel synthesizer, MIC


Edition: Volume 3 Issue 10, October 2014,


Pages: 1828 - 1832


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How to Cite this Article?

Aayushi Sharma, D. P. Pathak, "Synthesis, Characterization and Antimicrobial Activity of various Chalcone Derivatives", International Journal of Science and Research (IJSR), Volume 3 Issue 10, October 2014, pp. 1828-1832, https://www.ijsr.net/get_abstract.php?paper_id=OCT14586

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