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Research Paper | Chemistry | Iraq | Volume 5 Issue 3, March 2016
Synthesis, Characterize and Antimicrobial Study of New Chalcones and Pyrazole Derivatives from Progesterone
Nisreen Kais Abood | Hiba Hayder Ibraheem
Abstract: The aim of this work synthesized a new series of chalcones and pyrazole derivatives from the progesterone, the new steroidal synthesized by the claisen-Schmidt condensation reaction, were react progesterone with different aromatic substituted aldehyde in presence sodium hydroxide afforded chalcones derivatives (1-6). Cyclized the chalcone derivatives by reaction with hydrazine hydrate to afforded pyrazole derivatives (7-12). All synthesized compounds were characterized by measurement melting point, FT-IR spectral, Elemental Analysis and some of them by 1H-NMR spectral and Antimicrobials activities.
Keywords: Progesterone, Chalcone, Pyrazole, Antimicrobial, Biological activity
Edition: Volume 5 Issue 3, March 2016,
Pages: 833 - 836
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Research Paper, Chemistry, India, Volume 11 Issue 7, July 2022
Pages: 125 - 132Synthesis, Characterization and In Vitro Antimicrobial Evaluation of Some New Benzofuranyl Substituted Pyrido [3, 2-C] Coumarins
Nehakumari N. Gohil | D. I. Brahmbhatt
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Research Paper, Chemistry, India, Volume 10 Issue 2, February 2021
Pages: 1692 - 1697