International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 123

Research Paper | Chemistry | India | Volume 5 Issue 4, April 2016


Spectroscopic Investigation on the Interaction between 4-Amino Salicylic Acid (PAS) with Bovine Serum Albumin (BSA)

Mamali Priyadarshinee | Bairagi C. Mallick [2]


Abstract: PAS (4-amino salicylic acid) is a potentialantimicrobial drug used for the treatment of Mycobacterium tuberculosisdrug resistance. Its interaction with bovine serum albumin (BSA) is important to understand the mechanism of drug-protein interactions and its effectiveness to treat the drug resistance. The binding of PAS with BSA, investigatedby UV-visible and fluorescence measurements clearly indicates the conformational stability of the protein, Further, FT-IR and CD spectroscopic methods support the results with inceasing secondary structure content of the protein in the presence of drug.


Keywords: Bovine serum albumin BSA, 4-aminosalicylic acid PAS, fluorescence, FT-IR and CD spectroscopy


Edition: Volume 5 Issue 4, April 2016,


Pages: 573 - 576


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Mamali Priyadarshinee, Bairagi C. Mallick, "Spectroscopic Investigation on the Interaction between 4-Amino Salicylic Acid (PAS) with Bovine Serum Albumin (BSA)", International Journal of Science and Research (IJSR), Volume 5 Issue 4, April 2016, pp. 573-576, https://www.ijsr.net/get_abstract.php?paper_id=NOV161826

Similar Articles with Keyword 'fluorescence'

Downloads: 110

Research Paper, Chemistry, Egypt, Volume 4 Issue 7, July 2015

Pages: 1748 - 1755

New Spectrophotometric and Spectrofluorimetric Methods for Determination of Prazosin HCl in API and Drug Product

Hanan M. Elwy | Taghreed A. Mohammed

Share this Article

Downloads: 111

Research Paper, Chemistry, Iraq, Volume 3 Issue 11, November 2014

Pages: 2133 - 2138

Modification of the Photocatalytic Activity of Zinc Oxide by Doping Silver

Amjed M. Odeh | Ahmed S. Ferhod | Abbas J. Lafta [3]

Share this Article
Top