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Research Paper | Medicine | India | Volume 2 Issue 3, March 2013
Spectroscopic and DNA Binding Studies on a Novel Water Soluble Binuclear Copper (II) Schiff base
Wahengbam Bembee Devi [2] | R. K. Bhubon Singh [2]
Abstract: A novel water soluble binuclear copper (II) Schiff base complex have been synthesized by template condensation reaction method using 1, 2-diamino-2-methylpropane, furfural and copper (II) nitrate trihydrate in methanol. The newly prepared complex was characterized by elemental analyses, FT-IR, electronic spectra (UV-Vis) and thermogravimetric analysis techniques and was found to be water soluble. EPR study in room temperature as well as in frozen (77 K) dmso solution clearly indicates the complex is binuclear in nature. A DNA binding study by spectroscopic, cyclic voltammetry and viscosity measurement studies suggests the said complex is an avid binder to Calf Thymus DNA.
Keywords: water soluble, Schiff base cooper (II) complex, EPR, DNA binding
Edition: Volume 2 Issue 3, March 2013,
Pages: 143 - 147
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