International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 120

Case Studies | Pathology | India | Volume 8 Issue 8, August 2019


Primary CNS Lymphoma: An Institutional Study

Subhashree.S Dash | Soudamini Mahapatra [3] | Asaranti Kar [5]


Abstract: Introduction: Primary central nervous system lymphoma (PCNSL) is a rare group of extra nodal non-Hodgkin’s lymphomas. It accounts for 2.4-3 % of all brain tumours. Aim & Objectives: To study the clinicopathological & immunohistochemistry profile of patients with PCNSL presented between the years 2010 to 2019 in a tertiary care centre. Materials and Methods: This was a retrospective study. Clinical data were obtained from the hospital clinical case records. All the histopathologically proven cases of PCNSL involving the cerebral parenchyma were considered. All cases were studied in H & E then subjected to immunohistochemistry for LCA, CD20, CD3, GFAP and MIB1. Possibility of secondary involvement by a systemic lymphoma was excluded in every case. Statistical analysis was done by chi square test. Results: There were a total of 41 cases with median age of presentation being 52 years and with a male to female ratio1.15: 1. Headache was the most common presenting complaint. All patients were immunocompetent. Frontal lobe was the most common site of involvement. Diffuse large B cell lymphoma (DLBCL) was the histological pattern in all cases. Conclusion: All the patients were immunocompetent, association of PCNSL cases with HIV or acquired immunodeficiency syndrome was not found in our study. DLBCL constituted the majority of PCNSLs.


Keywords: Primary central nervous system lymphoma, diffuse large B-cell lymphoma, immunophenotyping


Edition: Volume 8 Issue 8, August 2019,


Pages: 1000 - 1003


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Subhashree.S Dash, Soudamini Mahapatra, Asaranti Kar, "Primary CNS Lymphoma: An Institutional Study", International Journal of Science and Research (IJSR), Volume 8 Issue 8, August 2019, pp. 1000-1003, https://www.ijsr.net/get_abstract.php?paper_id=ART2020463

Similar Articles with Keyword 'Primary'

Downloads: 0

Case Studies, Pathology, India, Volume 11 Issue 7, July 2022

Pages: 432 - 435

Primary Cutaneous Carcinosarcoma: A Rare Case Report with Review of Literature

Kavita Mardi [4] | Tenzin Lhanze Dingyon [4]

Share this Article

Downloads: 1

Case Studies, Pathology, India, Volume 10 Issue 8, August 2021

Pages: 1133 - 1135

Bilateral Breast Primary Tuberculous Mastitis a Rare Entity in Males - Case Report

Dr Shailendra Munj | Dr Krupa Jog | Dr Varsha Munj

Share this Article
Top