Saisreenivas U V, Uma Shanker, Uma Maheswarao T
Abstract: Majority of mesenchymal tumors of gastrointestinal tract are Gastrointestinal Stromal Tumor (GIST). It is, however, a rare tumor, accounting for less than 1 % of primary gastrointestinal (GI) neoplasms. Though, these tumors are refractory to conventional chemotherapy or radiotherapy but show a good response to targeted adjuvant chemotherapy with tyrosine kinase inhibitors following surgical resection. we report here a case of primary Extra-GIST tumor arising from mesentry of small bowel near duodeno-jejunal junction in a 40 years old male patient. The patient presented with distension in upper abdomen for past 3 months. On surgical intervention a mass was found involving mesentery 20 cm from duodenojejunal junction without involvement of gastrointestinal tract. Complete surgical resection of the tumor was done. Patient was discharged on 12th of post-operative day with advice of regular follow-up. GIST occurrence is not restricted to bowel but can involve unusual sites also. The mainstay of treatment remains surgical re- section with adequate margin.
Keywords: Extra-Gastrointestinal Stromal Tumors, GIST, Mesentric Tumors, Imatinib Mesylate