Carissa Lidia, I Wayan Gustawan, I Made Gede Dwi Lingga Utama, Ni Nengah Dwi Fatmawati
Abstract: Objective: To determine the characteristics of Staphylococcus aureus bloodstream infections among children. Method: A cross sectional study conducted in Pediatric Ward Sanglah Hospital. This study performed a retrospective review of medical records from pediatric patients who were proven to have Staphylococcus aureus infection through microbiological examination from blood culture samples while undergoing treatment. Result: There were total of 30 pediatric patients who were proven to have Staphylococcus aureus bloodstream infection. Nineteen (63 %) cases were male. The most common age group was 12-18 years old (36.7 %). Malnourished was found in 53 % of the patients. Malignancy, pneumonia, and chronic kidney disease were found in 8 (26.7 %), 5 (16.7 %), and 5 (16.7 %) subjects as the major comorbidities. Twenty three cases (76.7 %) were community-acquired infections while 7 cases (23.3 %) were hospital-acquired infections. The average length of stay before Staphylococcus aureus infection was 9.77 (SD 10.67) days with average total length of stay was 21.97 (SD 17.53) days. Most subjects used medical devices with an average duration of use of each medical device was more than 10 days. Antibiotics that were given before infection, most of the time, were Cefepime, Amikacin, and Cefixime with an average duration of use of each antibiotic was more than 7 days. Infections due to methicillin-resistant Staphylococcus aureus occured in two patients. Mortality rate for this study was 33 %. Conclusion: The majority of our patients were adolescents with malnourished in more than 50 % of cases. Malignancy, pneumonia, and chronic kidney disease as the major comorbidities in this study. Underlying medical conditions and medical devices used may be considered to be related to infection.
Keywords: Staphylococcus aureus infection, children