International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 123

Research Paper | Radiological Sciences | India | Volume 8 Issue 11, November 2019


Hippocampal Abnormalities in Adults with Unilateral Temporal Lobe Epilepsy: A Diffusion Tensor Imaging Study

Dr. P. Kalaivani | Dr. N. Sundareswaran


Abstract: Aims & objectives: To compare the fractional anisotropy and mean diffusivity of ipsilateral and contralateral hippocampus of unilateral temporal lobe epilepsy patients with age matched normal controls. Materials and methods: The study was conducted in the department of Radiology, Government Mohan Kumaramangalam Medical College, Salem. This study was done as an analytic, prospective case control study for a period of 3years from September 2016 to August 2019. Patients with a clinical picture of temporal lobe epilepsy, with either structural abnormalities in temporal lobe on MR imaging or EEG consistent with temporal lobe epilepsy were included. Our control group consisted of 30 adults. Imaging protocol: The examinations were performed in 1.5T Philips MRI system. Results: This study reveals increased mean diffusivity (ADC) and decreased fractional anisotropy (FA) in ipsilateral and contralateral hippocampi in patients with unilateral hippocampal sclerosis. Conclusion: In patients with clinical history of temporal lobe epilepsy and equivocal conventional MRI, significantly altered DTI values adds to the diagnosis.


Keywords: Diffusion tensor imaging, hippocampus, temporal lobe epilepsy


Edition: Volume 8 Issue 11, November 2019,


Pages: 1564 - 1572


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Dr. P. Kalaivani, Dr. N. Sundareswaran, "Hippocampal Abnormalities in Adults with Unilateral Temporal Lobe Epilepsy: A Diffusion Tensor Imaging Study", International Journal of Science and Research (IJSR), Volume 8 Issue 11, November 2019, pp. 1564-1572, https://www.ijsr.net/get_abstract.php?paper_id=ART20202997

Similar Articles with Keyword 'Diffusion'

Downloads: 114 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Case Studies, Radiological Sciences, India, Volume 3 Issue 8, August 2014

Pages: 1477 - 1480

A Rare Case of Adult-Onset Leukoencephalopathy with Brain Stem and Spinal Cord Involvement and Normal Lactate

Dr. Nihaal Reddy [2] | Dr. Harpreet Singh Grewal [2] | Dr. Santosh Patil

Share this Article

Downloads: 119

Research Paper, Radiological Sciences, India, Volume 5 Issue 7, July 2016

Pages: 2229 - 2232

Advances in Imaging of Vertebral and Spinal Cord Injury

Dr. Mitesh Ghadiali | Dr. Purvi Desai [7] | Dr. Rahul Sharma [4]

Share this Article
Top