Downloads: 158
Research Paper | Biochemistry | Nigeria | Volume 8 Issue 11, November 2019
Hypoglycemic Effects of Aqueous and Ethanolic Extracts of Leptadenia hastata on Streptozotocin-Induced Diabetes Mellitus in Albino Rats
Panuel B. | Nadro M.S. | Abbaya H.Y
Abstract: Single intra-peritoneal injection of 60 mg/kg body weight streptozotocin is known to induce diabetes mellitus and subsequently damage to the liver due to its hepato-toxic nature. The present study investigated the hypoglycemic and curative effects of Leptadenia hastata plant extracts conducted on 35 healthy male albino rats. The rats with blood glucose level above 200 mg/dl were randomly divided into seven (7) experimental groups of five rats each. Oral administration of 150 mg/kg body weight, 300 mg/kg body weight aqueous extract and 150 mg/kg body weight, 300 mg/kg body weight ethanolic extract were given to the diabetic rats for the period of 21 days. The fasting blood glucose was monitored at 7 days interval while markers of liver and kidney function were assayed at the end of 21 days treatment. The results revealed that oral administration of 300 mg/kg body weight ethanolic extract was found to be significant p
Keywords: Leptadenia hastata, Hypoglycemic effect, Diabetes mellitus, Streptozotocins
Edition: Volume 8 Issue 11, November 2019,
Pages: 152 - 158
Similar Articles with Keyword 'Diabetes mellitus'
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Masters Thesis, Biochemistry, India, Volume 11 Issue 8, August 2022
Pages: 859 - 863Assessment of Serum Amylase in Type-II Diabetes Mellitus Patients with a Putative Link to Pancreatic Function
Alisha Narula
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Analysis Study Research Paper, Biochemistry, India, Volume 12 Issue 5, May 2023
Pages: 2633 - 2635A Comparative Study of Glycated Hemoglobin and Serum Fructosamine, in Maturity Onset Diabetes Mellitus
Dr. Manish Chakrabarti