Verdu S, Mastrotta P, Nalli G
Abstract: Objective: The aim of this study is to determine the risk of HPV infection in stomatological lesions in the oral cavity. Study design: 53 patients over 21 years, who attended the Department of Oral Medicine of the School of Dentistry of the University of Buenos Aires, Argentina, who presented lesions in the oral cavity clinically compatible with HPV infection. Biopsies were performed in the affected areas and were divided in two parts, one for its histopathological diagnosis, and the other for its HPV determination. Statistical associations were analyzed using IBM Spss statistics V23 to obtain the Odds Ratio. Results: Of the total of the sample, HPV was positive in 60 % of the cases (32/53). The identified genotypes were of low risk (47 %) and high risk (53 %).HPV16 was the most common of the high risk group (35 %) and HPV11 was the most frequent type of the low risk group (53 %). Conclusion: We found an association between high-risk HPV and elevated white lesions present in oral mucosa. It is important to identify the type of HPV (high / low risk) present in stomatological lesions since its evolution will depend on this.
Keywords: Human Papillomavirus, Oral lesions, oral mucosa, Oral pathology, PCR