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Research Paper | Medicine Science | India | Volume 8 Issue 10, October 2019

Ocular Manifestations in Rheumatoid Arthritis and their Co-Relation with Anti Cyclic Citrullinated Peptide Antibodies

Dr. Indira Pegu | Dr. Bharoti S. Puzari | Dr. Sanjeeb Kakati | Dr. Gargi Choudhury ^[2]

Abstract: Aims & Objective: To study ocular manifestations in RA & co- relate with Anti CCP Ab. Materials & Method: 114 patients attending Rheumatology & Ophthalmology OPD of a tertiary care hospital were screened. Examination and tests: Detailed slit lamp examination, BCVA by Snellen's chart, IOP taken by Goldman's tonomerty. Schirmer's & ocular staining score done. Dilated fundus examined by IDO. Chi square test used to co - relate their significance & P value calculated. Results: 42.10 % (48) of 114 cases had ocular manifestation. Dry eye being commonest 31.57 % (36) followed by cataract in 6 (5.26%) of cases.1 case each of Sjogren's syndrome & scleritis.1.75% (2) cases had peripheral keratitis, anterior uveitis & episcleritis each. Strong association seen between presence of Anti CCP Ab & ocular manifestation by significant P value Conclusion: Ocular manifestations are significant extra articular manifestation. Flaring up of ocular manifestation may signal impending deterioration or relapse of RA.

Keywords: RA, Ocular manifestation, dry eye, Anti CCP antibodies

Edition: Volume 8 Issue 10, October 2019,

Pages: 755 - 761

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