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Research Paper | Microbiology | India | Volume 8 Issue 7, July 2019
Detection of Inducible Clindamycin Resistance and Methicillin Resistance in Staphylococcus species from Various Clinical Samples
Dr. Retina Paul | Lipika Pal | Risha Saha | Amrita Shaw
Abstract: Staphylococcus species is an important cause of nosocomial and community acquired infections worldwide. Clindamycin is an alternative agents used to treat Staphylococcal infections. Accurate identification of clindamycin resistance is important to prevent therapeutic failure. Unfortunately, inducible CL resistance is not detected by standard susceptibility tests. The aim of the present study was to detect the prevalence of inducible clindamycin and methicillin resistance among clinical isolates of Staphylococcal species via antibiotic sensitivity test. Total 129 Staphylococcal isolates were tested for antimicrobial susceptibility testing by as per guidelines. For detection of MRSA cefoxitin disc and for inducible clindamycin resistance, D test was performed. Out of 129 samples, 101 were Staphylococcus aureus and 28 were Coagulase negative Staphylococcus (CoNS). Out of which 61.3 % were MRSA and 38.6 % were MSSA. Inducible clindamycin resistant was detected in 30.6 % and MS phenotype in 42.7 %. D-test should be routinely performed for every Staphylococcus isolates otherwise clindamycin resistance may misinterpreted as clindamycin sensitive resulting in therapeutic failure.
Keywords: Staphylococcus aureus, Clindamycin resistance, MRSA
Edition: Volume 8 Issue 7, July 2019,
Pages: 1416 - 1419
Similar Articles with Keyword 'Staphylococcus aureus'
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Research Paper, Microbiology, Nigeria, Volume 9 Issue 6, June 2020
Pages: 742 - 745Isolation of Common Nosocomialpathogens from Gate Pass Used in Aminu Kano Teaching Hospital and Bayero University Kano, Nigeria
Umar Adamu Hamza [2] | Binta Muhammad Aminu | Muzammil Bashir Mustapha
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Student Project, Microbiology, India, Volume 11 Issue 10, October 2022
Pages: 668 - 672Screening of Antibacterial Activity of Cissus Quadrangularis and Boerhavia diffusa against Clinical Pathogens
K. Nandhini | J. Tharani | D. Sangeetha