International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 190

Research Paper | Biochemistry | India | Volume 8 Issue 5, May 2019


Evaluation of Association between Serum HS-CRP and Lipid Profile in Type 2 Diabetes Mellitus

Dr. Premjeet Kaur [2] | Dr. Naresh Malhotra


Abstract: High sensitive C-reactive protein (hs-CRP) is an established marker of low grade systemic inflammation. A chronic low-grade inflammatory condition has been proposed to underline increased risk for atherosclerotic disease, including renal dysfunction and cardiovascular disease suggesting a possible link between the high incidence of macrovascular complications and diabetes. Insulin resistance results in high concentrations of serum lipids in diabetics due to increased mobilization of free fatty acids from fat depots. Because serum hs-CRP and serum lipid profile reflect closely related component of the same disease process, a strong relationship between these variables may be anticipated. We selected 50 patients of Type-2 diabetes mellitus and 50 normal healthy individuals to evaluate this association. Serum estimations showed a significant increase (p< 0.001) in hs-CRP, Total cholesterol (TC), Triglycerides (TG), Low Density Lipoprotein (LDL) and Very Low Density Lipoprotein (VLDL) in diabetics when compared to controls. In contrast there was significant decrease (p< 0.001) in HDL-C in diabetics. The statistical analysis depicted a non significant correlation between serum hs-CRP and total cholesterol ( p= 0.909, r=0.017), serum triglyceride (p=0.294, r=0.151) and serum HDL (p=0.724, r=-0.051) in type 2 diabetic patients. This finding may therefore, suggest that hs-CRP act as an independent marker for cardiovascular risk factor.


Keywords: Type 2 diabetes diabetes, hs-CRP, lipid profile


Edition: Volume 8 Issue 5, May 2019,


Pages: 160 - 162


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Dr. Premjeet Kaur, Dr. Naresh Malhotra, "Evaluation of Association between Serum HS-CRP and Lipid Profile in Type 2 Diabetes Mellitus", International Journal of Science and Research (IJSR), Volume 8 Issue 5, May 2019, pp. 160-162, https://www.ijsr.net/get_abstract.php?paper_id=ART20197571

Similar Articles with Keyword 'lipid profile'

Downloads: 0

Research Paper, Biochemistry, India, Volume 11 Issue 4, April 2022

Pages: 535 - 538

A Comparative Study of Homocysteine, Cyanocobalamine, Folate, Lipid Profile and Serum Creatinine Level in Hypothyroid Subjects before and During Treatment

Kamlesh Tanwani [2] | Deepa Thadani [4] | Sarla Mahawar [4]

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Comparative Studies, Biochemistry, India, Volume 13 Issue 2, February 2024

Pages: 1841 - 1843

A Study of Serum C - Reactive Protein, Uric Acid and Lipid Profile in Patients with Psoriasis Visiting Dermatology Department, PBM Hospital, Bikaner

Dr. Neha Suthar

Share this Article
Top