Downloads: 131
Review Papers | Diabetology | India | Volume 8 Issue 1, January 2019
Role of Empagliflozin and Linagliptin Combination in Diabetic Kidney Disease
Sneha Thakur | Bhavesh Lalan | Amit Bhargava
Abstract: Chronic kidney disease (CKD) is a common comorbidity in type 2 diabetes mellitus (T2DM). It has been documented that CKD is associated with an increased risk of CVD and this further increases the mortality rate in T2DM by 2-3-fold. The current need is of a comprehensive approach to T2DM with concomitant renal disease. Scientific literature recommends early use of combination therapy in T2DM patients with a high risk of renal impairment. Considering the recent guidelines and published data on renal benefits with empagliflozin and linagliptin, combination therapy with these two agents may be a promising option in preventing and delaying the progression of renal impairment in T2DM patients. This review highlights the clinical evidence and the possible mechanisms for renal benefits with empagliflozin and linagliptin.
Keywords: T2DM, CKD, combination therapy, Empagliflozin, Linagliptin
Edition: Volume 8 Issue 1, January 2019,
Pages: 1333 - 1337
Similar Articles with Keyword 'T2DM'
Downloads: 4 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Diabetology, India, Volume 12 Issue 8, August 2023
Pages: 2350 - 2355A Comparative Retrospective Study of Vildagliptin 100mg SR OD and Sitagliptin 100 mg in Subjects with Type 2 Diabetes Mellitus
Dr. K. Vamsi Krishna | Dr Sanjeet Kumar Jaiswal | Dr Subodh Jain | Dr Syed Haroon Iqubal | Dr. Sona Warrier | Dr. Ashish Prasad | Dr. Ashish Birla | Mr. Vinod More | Dr. Ravindra Mote
Downloads: 76
Case Studies, Diabetology, India, Volume 7 Issue 1, January 2018
Pages: 1446 - 1449A Case of Diabetes Mellitus in A Young Adult ? An Unusual Presentation - Prader Willi Syndrome
Riyas R S | Soumik Goswami | Nilanjan Sengupta | Pranab Kumar Sahana | Arjun Baidya | Arindam Roy [2]