Downloading: Validated Spectrophotometric Method Development for Strontium Ranelate from Newly Developed Floating Tablet Formulation
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



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Validated Spectrophotometric Method Development for Strontium Ranelate from Newly Developed Floating Tablet Formulation

Dhanashree S Chavan, Sachin A Pishawikar, Harinath N. More, Suresh G. Killedar

In Present work, successful development of a simple, sensitive, rapid, accurate and precise spectrophotometric method has been done for the estimation of strontium ranelate in bulk and pharmaceutical dosage forms. The wavelength maxima for strontium ranelate was found to be 323 nm. Beers law was obeyed in the concentration range of 5-50 g/ml. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.2263 g/ml and 0.68 g/ml, respectively. The percentage recovery of the drug for the proposed method ranged from 96.86-104.54 % indicating no interference of the tablet excipients. The result of analysis were validated as per ICH guidelines [Q2 (R1) ].

Keywords: Strontium ranelate, UV spectrophotometry, Percentage recovery, Method development, Method validation

Edition: Volume 7 Issue 1, January 2018

Pages: 634 - 637

ART20178757



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