Downloads: 115
Research Paper | Dental Science | Iraq | Volume 6 Issue 11, November 2017
Micro Pericytes Coverage in Relation to Different Grades of Oral Squamous Cell Carcinoma
Intisar Abdel-Jabbar Al-Sarraf | Ban F. Al-Dorobai
Abstract: Background Angiogenesis is an important step in Oral Squamous Cell Carcinoma (OSCC) growth, progression, and metastasis. Micro Vessel Density (MVD) can reflect the angiogenic rate but not gives knowledge about the efficiency state of newly formed vessels. Measuring of micro vessel pericytes coverage index (MPI) for these blood vessels can determine the degree of their maturation. Aim of the study this study established to determine the association of between MVD, MPI and clinicopathological parameter of OSCC. Material and Methods Retrospective 36 formalin- fixed, paraffin-embedded tissue blocks histologically diagnosed as OSCC were examined for MVD and MPI were assessed by conventional immunohistochemistry staining using anti-CD105 and anti -SMA antibodies respectively. Results Highly significant association of MPI and histological grade of OSCC (P=0.000), while no significant difference between MVD and clinicopathological parameter of OSCC. Conclusion Both of MVD (using CD105) and MPI can considered as signs of the angiogenic and functional status of a tumor vascularity.
Keywords: Oral Squamous Cell Carcinoma, Pericytes, Micro Vessel Density
Edition: Volume 6 Issue 11, November 2017,
Pages: 2213 - 2216
Similar Articles with Keyword 'Oral Squamous Cell Carcinoma'
Downloads: 4 | Weekly Hits: ⮙3 | Monthly Hits: ⮙3
Doctoral Thesis, Dental Science, India, Volume 12 Issue 6, June 2023
Pages: 1762 - 1767Assessment of Human Telomerase Reverse Transcriptase Expression in Different Grades of Oral Epithelial Dysplasias and Oral Squamous Cell Carcinomas: An Immunohistochemical Study
Dr. Aritra Bhaumik | Dr. Sayani Shome | Dr. Anurag Nath
Downloads: 112
Review Papers, Dental Science, India, Volume 6 Issue 5, May 2017
Pages: 2659 - 2663Role of Anticancer Drugs in the Treatment of Oral Carcinomas-A Review of Literature
Sruthi Srinivasan | Dhanraj [15]