Prevalance of Hyperprolactinemia in PCOS

Dr. Swathi.T | Dr Sujaya V Rao

Abstract: Chronic anovulation is the most common finding in both polycystic ovary syndrome (PCOS) and hyperprolactinemia. PCOS is the most common endocrine disorder encountered among women at reproductive age group (18-35years) of age. PCOS diagnosed by Hyperandrogenesim ( hirsutism and or hyperandrogenemia), Ovarian dysfunction ( oligo/anovulation and polycystic ovaries) and exclusion of other androgen excess or related problems. Hyperprolactinemia is observed in about 5-10 % of women with amenorrhea, which is sometimes assosciated with galactorrhoea. Objectives of the present study were to identify the incidence of hyperprolactinemia in PCOS patients. Material and methods The study was conducted at Father Muller Medical College & Hospital, June 2016 December 2016. The subjects for the study were selected from patients attending department of Obstetrics and Gynaecology. The study was carried out on 52 women diagnosed to have PCOS using the Rotterdam criteria after an informed consent. Patients were advised to come overnight fasting and blood sample was drawn to measure the serum prolactin levels. Inclusion criteria Age 15 to 40 years of age Diagnosis of PCOS according to Rotterdam criteria in the presence of two of the following oligomenorrhea/amenorrhea/anovulation, hyperandrogenism, ultrasound diagnosed PCOS. Exclusion criteria any endocrine or gynaecological disorders Informed consent was obtained from all the participants. Normal prolactin levels 4.78 23.3ng/ml. The study group had no galactorrhea. RESULTS In our study the age group of the cases ranges from 18-35years of age. Mean age of the group is 24.61years. Prolactin levels compared in the study group, had mean prolactin levels of 21.51ng/ml. In the study 41 of the patients had prolactin levels 23.3. P value of 0.509 CONCLUSION As per this study we conclude that the incidence of hyperprolactinemia in women with PCOS is around 21 %. So here by we conclude that hyperprolactinemia and PCOS are two different entities. And hence, there is need to evaluate women with hyperprolactinemia when presented with menstrual disturbances.

Keywords: PCOS, Prolactin

Edition: Volume 6 Issue 11, November 2017,

Pages: 185 - 187