International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 137

Research Paper | Chemistry | India | Volume 6 Issue 8, August 2017


Isolation, Identification and Anti-Diabetic Activity of Isorhamnetin-3-O-?-L-(3??-E-p-coumaroyl)-Rhamnoside from Solanum torvum

Kannan Thangaiyan | Srinivasan Ramanujam


Abstract: To isolate a flavonoid glycoside from flowers of Solanum torvum using chromatography separation techniques, spectral characterization and its anti-diabetic activity. The structure of the isolated compound was purified, analyzed and characterized by chemical tests, HPLC and spectroscopic methods such as UV, IR, 1H-NMR and 13C-NMR. HPLC analysis exhibited the presence of a flavonol glycoside and its identified peak with the retention time of 26.8 min and showed two major peaks at 340 nm (band-I) and 260 nm (band-II). The flowers of Solanum torvum have been found to contain isorhamnetin-3-O--L- (3-E-p-coumaroyl) -rhamnoside. The blood sugar level was measured by digital display glucometer. The highest activity of Solanum torvum flower extract in this experiment was observed at the dose of 200 mg / kg of isolated compound while the reference drug glibenclamide (10 mg/kg) had a greater activity when associated with Solanum torvum flower extract.


Keywords: Anti-diabetic activity, isorhamnetin-3-O--L- 3-E-p-coumaroyl -rhamnoside, Solanum torvum, HPLC


Edition: Volume 6 Issue 8, August 2017,


Pages: 287 - 293


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Kannan Thangaiyan, Srinivasan Ramanujam, "Isolation, Identification and Anti-Diabetic Activity of Isorhamnetin-3-O-?-L-(3??-E-p-coumaroyl)-Rhamnoside from Solanum torvum", International Journal of Science and Research (IJSR), Volume 6 Issue 8, August 2017, pp. 287-293, https://www.ijsr.net/get_abstract.php?paper_id=ART20174080

Similar Articles with Keyword 'Antidiabetic activity'

Downloads: 115

Research Paper, Chemistry, India, Volume 6 Issue 2, February 2017

Pages: 1616 - 1620

Effect of Eclipta alba, Azadirachta indica, Pterocarpus Marsupium, Tinospora Cordifolia and Mangifera Indica Extracts on Experimentally Diabetic Induced Rats

Anjali Singh [8] | Ayodhya Singh [2] | Vandana Dwivedi [2]

Share this Article

Downloads: 133

Research Paper, Chemistry, India, Volume 5 Issue 7, July 2016

Pages: 470 - 476

Hypoglycemic Potential of Ascidia sydneiensis Stimpson, 1855 in Alloxan Induced Diabetic Rats

C. Stella Packiam | R. Jothibai Margret | V. K. Meenakshi [2]

Share this Article
Top