International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Review Papers | Biochemistry | India | Volume 6 Issue 5, May 2017


Angiogenic Biomarkers of Dysfunctional Uterine Bleeding

Ketki K [2] | Shailesh Kumar [7]


Abstract: Disturbed endometrial angiogenesis plays a role in the mechanism of Dysfunctional uterine bleeding (DUB). Under hypoxic conditions, Hypoxia inducible factor 1 alpha (HIF-1) rapidly accumulates and activates angiogenic growth factors, receptors and extracellular proteases such as matrix metalloproteinases (MMPs) like MMP-9. Copper influences the production of number of angiogenic factors including HIF-1.


Keywords: Angiogenesis, Dysfunctional uterine bleeding DUB, Hypoxia inducible factor 1 alpha HIF-1, Matrix metalloproteinase -9 MMP-9, Copper, Vascular endothelial growth factor VEGF


Edition: Volume 6 Issue 5, May 2017,


Pages: 2127 - 2132


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How to Cite this Article?

Ketki K, Shailesh Kumar, "Angiogenic Biomarkers of Dysfunctional Uterine Bleeding", International Journal of Science and Research (IJSR), Volume 6 Issue 5, May 2017, pp. 2127-2132, https://www.ijsr.net/get_abstract.php?paper_id=ART20173820

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