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Research Paper | Mathematics | Morocco | Volume 6 Issue 4, April 2017
The Optimal Impulsive Drug Schedule for Cancer Immunotherapy
Samira Zouhri | Smahane Saadi | Amine Hamdache
Abstract: The aim of this work is to resolve the problem of finding the optimal therapeutic protocols in cancer immunotherapy including the best dosage and timing of immunotherapy drug. We formulate this problem as an optimization problem by applying the theory of optimal impulsive control using a mathematical model of five ordinary differential equations that describe the kinetics of several populations (tumor cells and three types of immune cells) as well as the intervention of immunotherapy with interleukin2.
Keywords: immunotherapy Interleukin-2 impulsive optimal control drug schedule
Edition: Volume 6 Issue 4, April 2017,
Pages: 1643 - 1652
Similar Articles with Keyword 'impulsive'
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Research Paper, Mathematics, Libya, Volume 11 Issue 1, January 2022
Pages: 1366 - 1371The Oscillations for Delay Impulsive Fractional Partial Differential Equations (IFPDEs)
Suzan. A. A. Abu-harbid | Kholoud W. Saleem | Salima Kh. Ahmed
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Research Paper, Mathematics, Kenya, Volume 11 Issue 4, April 2022
Pages: 1 - 8Numerical Investigation of Hydromagnetic Natural Convection Flow of Heat Absorbing Fluid Past an Impulsively Moving Infinite Vertical Plate in the Presence of Uniform Transverse Magnetic Field
Bala Erick | Johana K. Sigey [6] | Jeconia A. Okelo [3] | Emmah Marigi [2]