International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 119

Research Paper | Medicine Science | Iraq | Volume 6 Issue 3, March 2017


The Effect of Vitamins B on Myelination of Injured Peripheral Nerve in Rat

Dr. Saleh M. Al-saaeed [2] | Dr. Maan H. Al-khalisy [2]


Abstract: Introduction Neuropathy is one of the common neurological problem which is cause by many factors, one of these factors is trauma. Traumatic neuropathy affects myelin sheath with or without nerve fiber. Demyelination includes disintegration of myelin sheath and myelin nucleus. Many medications have been used to treat traumatic neuropathy. One of these medications is vitamin B. Aim of the study Effect of vitamins B on myelination of degenerative traumatic neuropathy. Material and Method Forty albino rats were used in this study. All the animals exposed to crush injury of the sciatic nerve. These experimental animals were divided into 4 groups. Three of them received one type of vitamins B including vitamin B1, B6, B12 besides, the forth group received placebo. After 6weeks of experiments, crushed area of sciatic nerve was studies histologically and immunohistochemically. Result The group of animals, Which exposed to crush injury of sciatic nerve and treated with vitamin B12 revealed best regenerative process more than that which received B1 which in turn elicited better result than that group received vitamin B6. Discussion Vitamin B12 has a positive effects on myelination of nerve fiber, therefore it processed better regenerative reaction than that treated with vitamins B1 and B6.


Keywords: Vitamin B, Myelination, Nerve, rat


Edition: Volume 6 Issue 3, March 2017,


Pages: 2416 - 2420


How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF


How to Cite this Article?

Dr. Saleh M. Al-saaeed, Dr. Maan H. Al-khalisy, "The Effect of Vitamins B on Myelination of Injured Peripheral Nerve in Rat", International Journal of Science and Research (IJSR), Volume 6 Issue 3, March 2017, pp. 2416-2420, https://www.ijsr.net/get_abstract.php?paper_id=ART20172051

Similar Articles with Keyword 'Vitamin B'

Downloads: 114

Research Paper, Medicine Science, India, Volume 4 Issue 1, January 2015

Pages: 1332 - 1335

Study of Serum Folic Acid and Vitamin B12 levels in Patients of Vascular Dementia

N. Surendra Naik | Shashikala Lamani

Share this Article

Downloads: 120

Research Paper, Medicine Science, India, Volume 4 Issue 6, June 2015

Pages: 1980 - 1983

The Role of Serum Vitamin B12 and Homocysteine in Recurrent Pregnancy Loss

Vasudha Sawant [2] | Ajit Patil | Shweta Patki

Share this Article
Top