Analysis of GSTM1 Deletion on Adult Pulmonary Tuberculosis Patients
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064



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Research Paper | Medicine Science | Indonesia | Volume 6 Issue 1, January 2017

Analysis of GSTM1 Deletion on Adult Pulmonary Tuberculosis Patients

I Gusti Ayu Artini, I Gusti NgurahBagus Artana

It has been widely known that tuberculosis treatment might cause mild to severe side effects. One of which is hepatotoxic effect, that might potentially serious and might cause acute liver failure. Hepatoxicity incidence in worldwide has reached 48 % in many countries. One of the responsible factor contributing to this is genetical variation on drug metabolizing enzyme for antituberculosis, including GSTM1. Unfortunately, theres no enough evidence regarding distribution of GSTM1 deletion in Indonesia. Meanwhile, the proportion of GSTM1 null in many countries were varies, reached 43-46 %. This study aimed to identify the deletion of GSTM1 on tuberculosis patient receiving antituberculosis. GSTM1 deletion identification was conducted using PCR techniques. The proportion of GSTM1 null genotype in this study was 71.4 %.

Keywords: GSTM1 null, deletion, antituberculosis liver injury

Edition: Volume 6 Issue 1, January 2017

Pages: 1852 - 1853

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How to Cite this Article?

I Gusti Ayu Artini, I Gusti NgurahBagus Artana, "Analysis of GSTM1 Deletion on Adult Pulmonary Tuberculosis Patients", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=ART20164585, Volume 6 Issue 1, January 2017, 1852 - 1853

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Research Paper, Medicine Science, Indonesia, Volume 6 Issue 1, January 2017

Pages: 1852 - 1853

Analysis of GSTM1 Deletion on Adult Pulmonary Tuberculosis Patients

I Gusti Ayu Artini, I Gusti NgurahBagus Artana

Share this Article

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Research Paper, Medicine Science, Indonesia, Volume 6 Issue 1, January 2017

Pages: 1852 - 1853

Analysis of GSTM1 Deletion on Adult Pulmonary Tuberculosis Patients

I Gusti Ayu Artini, I Gusti NgurahBagus Artana

Share this Article



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