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Research Paper | Medical Surgical | India | Volume 6 Issue 1, January 2017

A Study to Find out Utility of Estimation of Serum CPK-NAC in Diagnosis and Prognosis of Electric Burn Induced Muscle Injury

Gupta Neelkamal | Sharma Brijesh Kumar | Gupta Ritu ^[3]

Abstract: INTRODUCTION Electric burn injuries constitute an important, distinct and often poorly understood variety of trauma. Muscles carry the highest percentage of current due to their large cross sectional area. CPK-Nac is a muscle specific isoenzyme of creatinine phosphokinase which increases in injuries of skeletal muscles. Thus the study was planned to find out the utility of CPK-Nac estimation in diagnosis and prognosis of electric burn injuries. MATERIAL AND METHOD The present study was conducted on 32 patients of electric burn in Department of Surgery, Mahatma Gandhi Medical College & Hospital, Jaipur. The serum CPK-Nac levels were measured by enzymatic method in clinical laboratory of Biochemistry. RESULT AND DISCUSSION The highest rate of complication was seen in patients with CPK-Nac value >4000IU/L while the lowest rate of complication was seen in patients with CPK-Nac value 0-1000IU/L. CONCLUSION Estimation of CPK-Nac is simple, affordable, cost effective and available at most of laboratories so it should be included in the routine panel of investigations in every patient of electric burn as a diagnostic and prognostic index for evaluation of muscle injuries.

Keywords: CPK-Nac, Skeletal muscle, Electric burn, Creatinine phosphokinase, isoenzyme

Edition: Volume 6 Issue 1, January 2017,

Pages: 540 - 541

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