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Case Studies | Pathology | India | Volume 5 Issue 10, October 2016

Epthelial Myoepithelial Carcinoma: A Rare Salivary Gland Neoplasm

Sujata S Giriyan ^[9] | Akanksha Agrawal ^[2] | Purushotham Reddy ^[4] | Rajesh H Chandan

Abstract: OBJECTIVE Epithelial-Myoepithelial Carcinoma is a rare entity with an incidence of <0.5 % of all salivary gland neoplasms. Parotid gland is the commonest affected site (75 %) followed by submandibular gland (12 %) and minor glands in palate (7 %). Women, usually in seventh decade of life, are commonly affected. These tumors can recur locally following resection. Epithelial-Myoepithelial carcinoma presents as a solitary, bulky mass which gradually enlarges over several months. This tumor is biphasic, composed of double layered ducts having an inner lining of small cuboidal or low columnar cells i. e. epithelial component and an outer mantle of clear cells i. e. myoepithelial component. Epithelial-Myoepithelial Carcinoma of salivary gland is a low-grade malignancy with distinct morphological features, and requires a wider recognition for better management. CASE REPORT We describe a case of male patient who presented with a swelling behind the left ear and was clinically diagnosed as Pleomorphic adenoma of the parotid gland. On FNAC, a differential of Adenoid Cystic Carcinoma or Epithelial-Myoepithelial Carcinoma of parotid gland were given. Histo-pathology revealed Epithelial-Myoepithelial Carcinoma which was corroborated with Immunohistochemistry. CONCLUSION Epithelial-Myoepithelial Carcinoma is often misdiagnosed. Hence, a thorough pathological work-up is essential for establishing definite diagnosis so as to enable to execute appropriate and complete treatment.

Keywords: Salivary Glands, Epithelial-Myoepithelial Carcinoma, Immunohistochemistry

Edition: Volume 5 Issue 10, October 2016,

Pages: 896 - 899

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