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Case Studies | Radiological Sciences | India | Volume 6 Issue 8, August 2017

Role of MR Spectroscopy in the Evaluation of Intra Axial Brain Tumours

Dr. Anil U Madurwar ^[2] | Dr. P. Rohan Reddy | Dr. G. Harshini Reddy | Dr. Bhavani ^[2]

Abstract: Aims and objectives To determine biochemical markers of intraaxial brain tumors using MR spectroscopy. To evaluate role of MR spectroscopy in diagnosing and grading of intraxial brain with histopathological co-relation. To evaluate role of MR spectroscopy in determining the infiltrative nature of the intra axial brain tumor. Study Design Hospital based descriptive study. Materials and methods MRI of 30 patients with spectroscopy correlation during December 2014 to June 2016 was analysed. Results Out of 30 patients 42 were males and 8 of them were females. The sensitivity, specificity, PPV and NPV was calculated (in %). For Glioblastoma Multiforme it was 90.91, 87.5, 83.33, 93.33, for Anaplastic Astrocytoma it was 33.33, 95.83.50.92, for Diffuse Infiltrative/Astrocytoma it was 100, 96, 66.67, 100, for Oligodendroglioma it was 50, 100, 100, 96. .15, 96.3, for Gliomatosis Cerebri it was 100, 100, 100, 100, for Ependymoma it was 50, 100, 100, 96.15, for Medulloblastoma it was 100100, 100, 100, for Metastasis it was 100, 100, 100, 100, for Choroid plexux Papilloma it was 100, 100, 100, 100, and for Lymphoma it was 0, 96.15, 0, 96.15, respectively.

Keywords: MR spectroscopy, choline, myoinositol, creatinine, choline/creatinine ratio, brain tumor, gliomas, NAA/Cr ratios

Edition: Volume 6 Issue 8, August 2017,

Pages: 430 - 436

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