Downloading: Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064



To prevent Server Overload, Your Article PDF will be Downloaded in Next Seconds

Synthesis of a Novel Series of Dioxazolines by 1.3-Dipolar Cycloaddition between N-alkyl 5-Chloroisatin Derivatives and Nitrile Oxides

Z. Tribak, M.K. Skalli, O. Senhaji, Y. Kandri Rodi

Abstract: A new series of dioxazoline of 5-Chloroisatin derivatives has been designed and synthesized involving 1, 3-dipolar cycloaddition reaction, preceded by a simple N-alkylation reaction in phase-transfer catalytic conditions The regioselectivity of the reactions was ascertained by 1H, 13C NMR spectroscopy of the synthesized compounds.

Keywords: 5-Chloroisatin, Dioxazoline, N-alkylation, 1, 3-Dipolar cycloaddition, 1H, 13C NMR spectroscopy



Top