Abstract: The importance of influenza viruses as worldwide infectious agents is well recognized. The different subtypes of influenza A virus though they all are closely related, they have distinctly different pathogenic behavior which plays an important role in survival in different species. We concluded from phylogenetic analysis that from the common ancestor these strains are diverged more in the course of evolution. So as to adopt a far better survival strategy, this drift is a lot of outstanding. The purpose of modeling is to help the Drug developers and Biotechnologists to develop the drug more efficiently and with more effectiveness in future by analyzing the modeled structures of the protein.
Keywords: influenza, phylogeny, hemagglutinin, homology modeling