Nimisha Balakrishnan, Sendhilvadivu.M
Abstract: BPA is an estrogenic chemical produced in large quantities for use primarily in the production of polycarbonate and epoxy resins. The present study was conducted to estimate protein, lipid and TSH levels in serum of BPA induced and vitamin E supplemented rats. The physiological and biochemical activities in the albino rats were completely disturbed after the oral administration of BPA. The high dose of BPA induces serum damage affecting protein, total cholesterol and thyroid level as a result of reactive oxygen species in rat serum and cause damage and the condition is reversed by Vitamin E supplementation.
Keywords: BPA, Albino pregnant rat, Aminotranferases and GDH activity, Serum cholesterol, Immunohisto chemistry