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Research Paper | Medicine Science | India | Volume 4 Issue 1, January 2015
Comparison between Dexmedetomidine and Clonidine as an Adjuvant to Spinal Anesthesia in Abdominal Hysterectomy
Gunjan Jain [2] | Dinesh Chauhan | Grishma Chauhan | R.M. Upadhyaya
Abstract: INTRODUCTION Newer -2 agonist agents have opened a new chapter in prolongation of duration of neuraxial block and postoperative analgesia. MATERIAL AND METHODS Sixty adult patients of ASA grade I-II were randomly divided into two groups of thirty each. Group Dexmedetomidine and group Clonidine. All patients received hyperbaric bupivacaine 0.5 % (heavy) 15 mg intrathecally with dexmedetomidine 10 g and with clonidine 15 g respectively (30 each). Sensory block, motor block, intra-operative hemodynamic changes, two segment regression and total duration of analgesia was assessed. RESULT AND CONCLUSION Onset time of sensory and motor block was shorter in group D compared to group C. Two segment regression time was significantly higher in group D (100.67 17.798 min) as compared to group C (71.167 23.44 min). Total duration of analgesia was significantly prolonged in group D (97.73 27.43 min) as compared to Group C (32.33 21.96 min). Heart rate and mean arterial pressure remained at lower level in both groups but was not statistical significant. It can be concluded that though both clonidine and dexmedetomidine prolonged duration of sensory and motor block of bupivacaine, dexmedetomidine is better in terms of longer duration of action.
Keywords: Adjuvants, Dexmedetomidine, Clonidine, Hyperbaric Bupivacaine 05 % H, Spinal Anaesthesia
Edition: Volume 4 Issue 1, January 2015,
Pages: 2386 - 2389
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Research Paper, Medicine Science, India, Volume 8 Issue 10, October 2019
Pages: 1657 - 1660Comparison of Caudal Bupivacaine Alone with Dexmedetomidine as an Adjuvant with Bupivacaine for Post Operative Analgesia in Paediatric Patient Undergoing Inguinal Region Surgeries
Dr Pooja Agrawal | Dr Aishwarya Bandewar | Dr Olvyna D'souza
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Comparative Studies, Medicine Science, India, Volume 6 Issue 2, February 2017
Pages: 1154 - 1159A Comparison between Intrathecal Dexmedetomidine and Fentanyl as an Adjuvant to Hyperbaric Bupivacaine in Spinal Anaesthesia for Lower Limb Surgeries - A Double Blind Controlled Study
Gouranga Sikdar | Rita Haldar Dasgupta | Sujata Dalai