International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064




Downloads: 101

Informative Article | Meteorology Science | Albania | Volume 4 Issue 9, September 2015


First Cohort Study on Iron Chelation Therapy of Patients with Hemoglobinopathies Born from 1980-2014 Treated in the Main Diagnostic and Treatment Center of Hemoglobinopathies in Albania

Eleni NASTAS [2] | Mirela TABAKU | Altin MALAJ | Manika KREKA [2] | Mirela XHAFA [2] | Donjeta BALI [3] | Anila GODO [2]


Abstract: Albania is affected by thalassemia and hemoglobin disorders. Chronic transfusion therapy plays an important role in the management of them but, inevitably leads to iron overload, which requires chelation therapy. The chelation therapy was regularly initiated at our center on 1998. The aim of this paper is to present a data comparison of the mean serum ferritin level of thalassemia major, sickle cell disease and thalaso-sickle cell disease patients born between 1980- 1997 with that of patients born between 1998-2014, as well as, to estimate the mortality rate between these two groups. This is the first study done on this subject in Albania. A cohort of 358 multi blood transfused patients born between 1980 - 2014 was studied. There was a significant reduced number of patients with high serum level of ferritin in the group born after 1998, which got chelation therapy from the beginning. Comparison of 17-year year mortality rate shows that mortality was significantly lower for those born after 1998.


Keywords: thalassemia major, sickle cell disease, thalassemia sickle cell disease, chelation therapy, serum ferritin level, mortality rate


Edition: Volume 4 Issue 9, September 2015,


Pages: 1429 - 1432


How to Cite this Article?

Eleni NASTAS, Mirela TABAKU, Altin MALAJ, Manika KREKA, Mirela XHAFA, Donjeta BALI, Anila GODO, "First Cohort Study on Iron Chelation Therapy of Patients with Hemoglobinopathies Born from 1980-2014 Treated in the Main Diagnostic and Treatment Center of Hemoglobinopathies in Albania", International Journal of Science and Research (IJSR), Volume 4 Issue 9, September 2015, pp. 1429-1432, https://www.ijsr.net/get_abstract.php?paper_id=SUB158408

How to Share this Article?






Similar Articles with Keyword 'major'

Downloads: 92

Research Paper, Meteorology Science, Saudi Arabia, Volume 3 Issue 9, September 2014

Pages: 1324 - 1343

Recent Trends in Surface Air Temperature over Al-Taif, Saudi Arabia

Abdellatif Esawy A. Abdou [2]

Share this Article

Downloads: 133

Research Paper, Meteorology Science, India, Volume 5 Issue 3, March 2016

Pages: 357 - 362

Dynamics of Heavy Rain Spells over India during 2005

S. S. Naik | P. S. Salvekar [2]

Share this Article


Top