International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 114

Review Papers | Medical Surgical | India | Volume 4 Issue 8, August 2015


Crohn's Disease: A Literature Review

Dr. Prakash Galani [2]


Abstract: Crohns disease is a chronic relapsing inflammatory bowel disease that may affect any part of the gastrointestinal tract. The ileum, colon, and perineum are most commonly affected. It is characterised by transmural inflammation, and granulomata may be present. Whilst the aetiology of Crohns disease is not completely understood, it is thought to be caused by the complex interplay between genetic, immunological, microbiological, and environmental factors. It is multisystem disorder with potential for systemic and extraintestinal complications can affect any age group, but the onset is most common in the second and third decades. The most common symptoms of Crohns disease are diarrhoea, abdominal pain, weight loss, and fatigue. Symptoms reflect the site and behaviour of disease, and the presence or absence of strictures and fistulae. Treatment has changed radically over the past decade with the introduction of biological therapy and increased use of immunomodulators. Awareness of the therapeutic potential and associated adverse events is necessary both for offering benefit and for protecting patients from undue risks from these treatments.


Keywords: Crohns disease, diarrhea, ileum, immunomodulators


Edition: Volume 4 Issue 8, August 2015,


Pages: 1769 - 1771


How to Cite this Article?

Dr. Prakash Galani, "Crohn's Disease: A Literature Review", International Journal of Science and Research (IJSR), Volume 4 Issue 8, August 2015, pp. 1769-1771, https://www.ijsr.net/get_abstract.php?paper_id=SUB157775

How to Share this Article?

Enter Your Email Address




Similar Articles with Keyword 'Crohns disease'

Downloads: 99

Case Studies, Medical Surgical, India, Volume 7 Issue 8, August 2018

Pages: 1191 - 1192

Transverse Colon Stricture due to Kochs - A Rare Case Report

Dr. Priya Ahire | Dr. Rukmini P. Waghmare | Dr. Prachiti Gokhe | Dr. Mukund B. Tayade

Share this Article

Downloads: 120

Case Studies, Medical Surgical, India, Volume 6 Issue 5, May 2017

Pages: 1405 - 1407

An Unusual Presentation of Crohn's Disease - A Case Report

Jain A [6] | Bhat M | Khan S [6] | Dangayach KK

Share this Article


Top