Research Paper | Chemistry | Pakistan | Volume 4 Issue 7, July 2015
Antibacterial Activity of Some New Compounds of Sarcococcasaligna
Tahira Moeen Khan, Ismat Naeem
Abstract: Pharmacological studies of S. saligna revealed that the crude ethanolic extracts of S. saligna (aerial parts) and roots were cytotoxic and antibacterial but produced no platelet aggregation induced by ADP. Antibacterial activity of four alkaloids (compounds) was determined for the first time against 11 bacterial strains. Compound 1 (Sracosalgmine) showed moderate activity against Shigella boydii, Klebsiella pneumoniae. Compound 2 (Sracosalgminol) showed less activity with Staphylococuss aureus and Streptococus pyrogens. Compound 3 (sracosalgnenone) and Compound 4 (14-15 dehydrosarcovagine-D) were inactive against all bacterial strains
Keywords: Sarcococca saligna, Buxaceae, steroidal alkaloid, antibacterial alkaloid, Sracosalgmine, Sracosalgminol, Sracosalgnenone, 14-15 dehydrosarcovagine-D
Edition: Volume 4 Issue 7, July 2015,
Pages: 2527 - 2529
How to Cite this Article?
Tahira Moeen Khan, Ismat Naeem, "Antibacterial Activity of Some New Compounds of Sarcococcasaligna", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SUB157042, Volume 4 Issue 7, July 2015, 2527 - 2529
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