International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 117

Research Paper | Chemistry | Pakistan | Volume 4 Issue 7, July 2015


Antibacterial Activity of Some New Compounds of Sarcococcasaligna

Tahira Moeen Khan, Ismat Naeem


Abstract: Pharmacological studies of S. saligna revealed that the crude ethanolic extracts of S. saligna (aerial parts) and roots were cytotoxic and antibacterial but produced no platelet aggregation induced by ADP. Antibacterial activity of four alkaloids (compounds) was determined for the first time against 11 bacterial strains. Compound 1 (Sracosalgmine) showed moderate activity against Shigella boydii, Klebsiella pneumoniae. Compound 2 (Sracosalgminol) showed less activity with Staphylococuss aureus and Streptococus pyrogens. Compound 3 (sracosalgnenone) and Compound 4 (14-15 dehydrosarcovagine-D) were inactive against all bacterial strains


Keywords: Sarcococca saligna, Buxaceae, steroidal alkaloid, antibacterial alkaloid, Sracosalgmine, Sracosalgminol, Sracosalgnenone, 14-15 dehydrosarcovagine-D


Edition: Volume 4 Issue 7, July 2015,


Pages: 2527 - 2529


How to Cite this Article?

Tahira Moeen Khan, Ismat Naeem, "Antibacterial Activity of Some New Compounds of Sarcococcasaligna", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SUB157042, Volume 4 Issue 7, July 2015, 2527 - 2529

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