Review Papers | Medicine Science | India | Volume 4 Issue 7, July 2015
Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury
Anusha R, Madhubala V
Abstract: The treatment of kidney disease poses a major challenge to the health care system and the global economy. Hence the detection and management of kidney diseases in the early, reversible and potentially treatable stages is of paramount importance. AKI is largely asymptomatic and establishing the diagnosis relies on functional biomarkers such as serial serum creatinine measurements. Unfortunately, serum creatinine is a delayed and unreliable indicator of AKI. Animal studies have identified interventions that can prevent and/ or treat AKI if identified early in the course of disease, even before the serum creatinine begins to rise. The paucity of early biomarkers has hampered our ability to translate these promising therapies to human AKI. Fortunately, understanding the early stress response of the kidney to acute injury has revealed a number of potential biomarkers. Neutrophil Gelatinase Associated Lipocalin (NGAL) is one among them. This paper highlights the role of NGAL as a biomarker of AKI.
Keywords: AKI, biomarker, creatinine, early, NGAL
Edition: Volume 4 Issue 7, July 2015,
Pages: 1085 - 1090
How to Cite this Article?
Anusha R, Madhubala V, "Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SUB156508, Volume 4 Issue 7, July 2015, 1085 - 1090
How to Share this Article?
Similar Articles with Keyword 'AKI'
Hybrid Verrucous Carcinoma - A Case Report
Dr. Abhilasha Asthana, Dr. Amit Kumar Singh
A Radiographic Assessment of the Prevalence of Pulp Stones in Premolars Regarding the Dental Arches
Similar Articles with Keyword 'biomarker'
Possibility of Combined Assessment of Biomarkers in Early Parkinsons Disease
Dimitar Kochev, Julia Petrova, Maria Petrova, Dimo Krastev, Lachezar Traikov
Evaluation of Procalcitonin in Adult Patients with Fever
Edmond Puca, Arben Pilaca, Entela Y Puca, Gentian Stroni, Elda Qyra, Ilir Akshija, Gentian Huti, Anila Laurence, Arben Pepa, Pellumb Pipero
Similar Articles with Keyword 'creatinine'
Evaluate the Effect of Coenzymeq10 Supplementation on Reducing Oxidative Stress in Patients with Relapsing Remitting Multiple Sclerosis
Mariam Omran Waheed, Haider Al- Tukmagi, Ali Kadhim Kareem
Urinary Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) As a Marker for Lupus Nephritis Activity
Mohamed Elsayed, Khaled A. Elhefnawy, Anas A. Qassem, Ghada E. Amr
Similar Articles with Keyword 'early'
Marchiafava - Bignami Disease - A Case Report and a Brief Review of Literature
Dr. Vajed Mogal, Dr. Sarfaraz Mohammad, Dr. Amit Rathi, Dr. Kulin Seth
Autism and Seisures in Children Admitted in a Tertiary Hospital
Armand Shehu, Aida Bushati, Valentina Tashko
Similar Articles with Keyword 'NGAL'
Phaeohyphomycosis of the Foot Caused by Phaeoacremoniumrubrigenum in an Elderly Lady: Fungal Infection with a Tumour like Presentation
Noreen Fazlina Mat Nor, Sa'adon Ibrahim
A Case Control Study on the Risk Factors of Cervical Cancer among Women in a Coastal City of South India
Padma Mohanan, Soumya Shetty