Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Open Access | Fully Refereed | Peer Reviewed International Journal

ISSN: 2319-7064



Review Papers | Medicine Science | India | Volume 4 Issue 7, July 2015

Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury

Anusha R, Madhubala V

The treatment of kidney disease poses a major challenge to the health care system and the global economy. Hence the detection and management of kidney diseases in the early, reversible and potentially treatable stages is of paramount importance. AKI is largely asymptomatic and establishing the diagnosis relies on functional biomarkers such as serial serum creatinine measurements. Unfortunately, serum creatinine is a delayed and unreliable indicator of AKI. Animal studies have identified interventions that can prevent and/ or treat AKI if identified early in the course of disease, even before the serum creatinine begins to rise. The paucity of early biomarkers has hampered our ability to translate these promising therapies to human AKI. Fortunately, understanding the early stress response of the kidney to acute injury has revealed a number of potential biomarkers. Neutrophil Gelatinase Associated Lipocalin (NGAL) is one among them. This paper highlights the role of NGAL as a biomarker of AKI.

Keywords: AKI, biomarker, creatinine, early, NGAL

Edition: Volume 4 Issue 7, July 2015

Pages: 1085 - 1090

Share this Article

How to Cite this Article?

Anusha R, Madhubala V, "Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SUB156508, Volume 4 Issue 7, July 2015, 1085 - 1090

56 PDF Views | 51 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'AKI'

Case Studies, Medicine Science, India, Volume 3 Issue 10, October 2014

Pages: 1042 - 1044

Hybrid Verrucous Carcinoma - A Case Report

Dr. Abhilasha Asthana, Dr. Amit Kumar Singh

Share this Article

Research Paper, Medicine Science, Nigeria, Volume 3 Issue 12, December 2014

Pages: 2723 - 2726

Giant Inguinal Hernia: Our Experience in Maiduguri, North Eastern Nigeria

A. G. Ibrahim, S. Aliyu, B. S. Mohammed

Share this Article

Survey Paper, Medicine Science, Bulgaria, Volume 4 Issue 1, January 2015

Pages: 1088 - 1091

Prevalence of Dental Caries in Hearing Impaired Children than 5 to 12 Years Old in Sofia

Liliya Doichinova, Milena Peneva

Share this Article

Review Papers, Medicine Science, Bulgaria, Volume 4 Issue 4, April 2015

Pages: 1449 - 1454

Non-Cpap Conservative Treatment Alternatives for Patients with Obstructive Sleep Apnea/Hypopnea Syndrome

Alexander Raynov MD PhD, Mario Milkov MD PhD, Milena Nikolova MD PhD, Krasimir Rankov MD, Julian Rangachev MD PhD

Share this Article

Research Paper, Medicine Science, Macedonia, Volume 4 Issue 7, July 2015

Pages: 1990 - 1993

Prevalence of Pulp Stones in Molars Regarding the Dental Arches

Pavlina Aleksova

Share this Article

Similar Articles with Keyword 'biomarker'

Case Studies, Medicine Science, Bulgaria, Volume 3 Issue 10, October 2014

Pages: 1332 - 1334

Possibility of Combined Assessment of Biomarkers in Early Parkinson's Disease

Dimitar Kochev, Julia Petrova, Maria Petrova, Dimo Krastev, Lachezar Traikov

Share this Article

Research Paper, Medicine Science, India, Volume 3 Issue 12, December 2014

Pages: 2377 - 2382

Inflammatory Biomarkers (Il-18, Hs-Crp) and Serum Lipids: A Novel Approach to Screen Early Diabetic Nephropathy

Dr. Yeshavanth G, Dr. Sachin Bongale

Share this Article

Research Paper, Medicine Science, Albania, Volume 3 Issue 12, December 2014

Pages: 2421 - 2424

Evaluation of Procalcitonin in Adult Patients with Fever

Edmond Puca, Arben Pilaca, Entela Y Puca, Gentian Stroni, Elda Qyra, Ilir Akshija, Gentian Huti, Anila Laurence, Arben Pepa, Pellumb Pipero

Share this Article

Review Papers, Medicine Science, India, Volume 4 Issue 7, July 2015

Pages: 1085 - 1090

Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury

Anusha R, Madhubala V

Share this Article

Research Paper, Medicine Science, Albania, Volume 4 Issue 8, August 2015

Pages: 1667 - 1669

New Laboratory Biomarkers for Early Diagnosis of Preeclampsia

Albana Daka, Anyla Bulo

Share this Article

Similar Articles with Keyword 'creatinine'

Research Paper, Medicine Science, India, Volume 3 Issue 6, June 2014

Pages: 1554 - 1556

Microfilariosis in Dogs - An Emerging Cause for Renal Failure

Ambily, V.R, Usha. N. Pillai

Share this Article

Research Paper, Medicine Science, Iraq, Volume 4 Issue 11, November 2015

Pages: 2262 - 2264

Evaluate the Effect of Coenzymeq10 Supplementation on Reducing Oxidative Stress in Patients with Relapsing Remitting Multiple Sclerosis

Mariam Omran Waheed, Haider Al- Tukmagi, Ali Kadhim Kareem

Share this Article

Review Papers, Medicine Science, India, Volume 4 Issue 7, July 2015

Pages: 1085 - 1090

Neutrophil Gelatinase Associated Lipocalin-Ngal: An Emerging Biomarker for Acute Kidney Injury

Anusha R, Madhubala V

Share this Article

Research Paper, Medicine Science, India, Volume 4 Issue 1, January 2015

Pages: 2763 - 2766

Epidemiology and Outcomes of Acute Renal Failure in Rural Females of Low Socioeconomic Status - A Referral Hospital Experience

Prasad Gullipalli, Ch. Nageswara Rao

Share this Article

Research Paper, Medicine Science, Egypt, Volume 5 Issue 7, July 2016

Pages: 1539 - 1544

Serum Kidney Injury Molecule-1 in Hepatorenal Syndrome at Medical Intensive Care Unit of Zagazig University Hospitals

Usama Khalil, Fayroz O Seliem, Ashraf Khalifa, Ayman M.E.M. Sadek, Mohammad S. Fawzi, Nermin Raafat

Share this Article

Similar Articles with Keyword 'early'

Case Studies, Medicine Science, India, Volume 4 Issue 5, May 2015

Pages: 3187 - 3190

Marchiafava - Bignami Disease - A Case Report and a Brief Review of Literature

Dr. Vajed Mogal, Dr. Sarfaraz Mohammad, Dr. Amit Rathi, Dr. Kulin Seth

Share this Article

Research Paper, Medicine Science, Albania, Volume 4 Issue 3, March 2015

Pages: 2213 - 2215

Autism and Seisures in Children Admitted in a Tertiary Hospital

Armand Shehu, Aida Bushati, Valentina Tashko

Share this Article

Case Studies, Medicine Science, Bulgaria, Volume 3 Issue 10, October 2014

Pages: 1332 - 1334

Possibility of Combined Assessment of Biomarkers in Early Parkinson's Disease

Dimitar Kochev, Julia Petrova, Maria Petrova, Dimo Krastev, Lachezar Traikov

Share this Article

Case Studies, Medicine Science, India, Volume 8 Issue 11, November 2019

Pages: 1667 - 1668

Kayser Fleischer Ring - An Early Indicator of Wilson's Disease - A Case Study

Mridula V Amarnath

Share this Article

Research Paper, Medicine Science, India, Volume 3 Issue 12, December 2014

Pages: 1115 - 1119

A Pilot Study to Compare Effects of Mannitol with Hypertonic Saline in Combination with HES on Blood Coagulation and Platelet Function during Elective Craniotomy

Vidhu Bhatnagar

Share this Article

Similar Articles with Keyword 'NGAL'

Research Paper, Medicine Science, India, Volume 4 Issue 5, May 2015

Pages: 1077 - 1080

Anatomical Variants of Circle of Willisin South Indian Population: A Study by Using Magnetic Resonance Angiography

Dr. Arjun Bahaddur, Dr. Chandan G

Share this Article

Research Paper, Medicine Science, India, Volume 5 Issue 10, October 2016

Pages: 1220 - 1221

A Study of Allergens

Dr Prashanth Kumar

Share this Article

Research Paper, Medicine Science, India, Volume 4 Issue 7, July 2015

Pages: 2049 - 2051

A Case Control Study on the Risk Factors of Cervical Cancer among Women in a Coastal City of South India

Padma Mohanan, Soumya Shetty

Share this Article

Research Paper, Medicine Science, India, Volume 6 Issue 6, June 2017

Pages: 1177 - 1178

A Study of Micronucleus in Tobacco Chewers and Tobacco Smokers

Dr Indira S Bangera

Share this Article

Research Paper, Medicine Science, India, Volume 5 Issue 10, October 2016

Pages: 1222 - 1223

A Study of Adverse Effects of Fluoroquinolones

Dr Prashanth Kumar

Share this Article
Top