Hyperglicemia IncreasedThe Expression of TLR2 mRNA and Coronin-1A Level in Lung Mice which were infected by Mycobacterium Tuberculosis
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



Research Paper | Medicine Science | Indonesia | Volume 4 Issue 6, June 2015

Hyperglicemia IncreasedThe Expression of TLR2 mRNA and Coronin-1A Level in Lung Mice which were infected by Mycobacterium Tuberculosis

Wande IN, Sutirta Yasa IWP, Linawati NM

The present study was conducted to evaluate the expression of TLR2 mRNA and Coronin-1A level in mice which were infected with Mycobacterium tuberculosis (M.tb) and hyperglycemia. A total of 24 mice were divided into 2 groups and all were infected with M.tb, then control group were injected of 5 l a sodium citrate buffer intraperitoneally and treatment group were injected 150 mg/kgbw streptozotocin (STZ) dissolved in 5 l sodium citrate buffer intraperitoneally to make hyperglycemia. Lung tissue harvesting conducted for RT-PCR examination for expression of TLR2 mRNA and Coronin-1A level at 3 and 5 week. In this study found the expression of TLR2 mRNA and Coronin-1A level in mice infected with M.tb and hyperglycemia which were examined in the fifth week were signifikan higher than others.

Keywords: TLR2 mRNA, Coronin-1A, Mycobacterium tuberculosis

Edition: Volume 4 Issue 6, June 2015

Pages: 2950 - 2952

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How to Cite this Article?

Wande IN, Sutirta Yasa IWP, Linawati NM, "Hyperglicemia IncreasedThe Expression of TLR2 mRNA and Coronin-1A Level in Lung Mice which were infected by Mycobacterium Tuberculosis", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SUB156073, Volume 4 Issue 6, June 2015, 2950 - 2952

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