International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064

Downloads: 103

Research Paper | Medicine Science | Bulgaria | Volume 4 Issue 4, April 2015

Is there a Marker to Predict Restenosis After Carotid Stenting?

Petova J | Manolov V [3] | Velchev V | Milev B | Vasilev V [3] | Tzatchev K [3] | Marinov B [3]

Abstract: BACKGROUND Carotid atherosclerosis is the leading cause of ischemic stroke. Carotid Arteria Stenting (CAS) is a technique for carotid occlusive disease treatment. CAS procedures are performing in patients with carotid stenosis. METHODS We include 241 patients after stroke and 126 with high-graded asymptomatic stenosis in arteria carotis were included, eighteen of them had lesion type I and twenty one with lesion type IV (after stenting). Their results were compared to 91 age matched healthy controls. Included patients and controls were diagnosed by history of diseases, clinically examination, with ultrasound and MRI investigation. Included groups were evaluated by total cholesterol, LDL-cholesterol, homocysteine, hsCRP, D Dimer. RESULTS We found a correlation between serum ADMA and homocysteine levels in patients with asymptomatic stenosis (r = 0.612), P < 0.001. It seems to be the leading factor for the stroke. In after stroke patients an important correlations are ADMA to homocysteine (r = -0.751), ADMA to LDL-cholesterol (r = 0.719), and ADMA to hsCRP (r = 0.543), P < 0.001. In patients with in-stent restenosis (ISR) injury and restenosis we found a correlation ADMA to total cholesterol (r = 0.509) and ADMA to RR systolic (r = -0.519), P < 0.001. CONCLUSIONS Serum ADMA levels, homocysteine, LDL-cholesterol and hsCRP concentrations in combination are useful for early identification of highly risked asymptomatic and symptomatic patients for restenosis, as well as patients after stenting of arteria carotis. Serum ADMA might be a new marker to predict early diagnosis of restenosis after carotid stenting.

Keywords: ADMA, restenosis, stroke, stent, ISR lesion

Edition: Volume 4 Issue 4, April 2015,

Pages: 3355 - 3359

How to Download this Article?

You Need to Register Your Email Address Before You Can Download the Article PDF

How to Cite this Article?

Petova J, Manolov V, Velchev V, Milev B, Vasilev V, Tzatchev K, Marinov B, "Is there a Marker to Predict Restenosis After Carotid Stenting?", International Journal of Science and Research (IJSR), Volume 4 Issue 4, April 2015, pp. 3355-3359,

Similar Articles with Keyword 'stroke'

Downloads: 107

Dissertation Chapters, Medicine Science, India, Volume 3 Issue 9, September 2014

Pages: 1481 - 1483

Assessment of Prescription Pattern Associated with Anti-Hypertensive Treatment at Tertiary Care Teaching Hospital in Central Karnataka

Kasi Jagadeesh M | Uday Kumar R.

Share this Article

Downloads: 109

Research Paper, Medicine Science, India, Volume 3 Issue 3, March 2014

Pages: 292 - 298

Effectiveness of Slow Back Massage on Quality of Sleep among ICU Patents

Mahadeo B Shinde [4] | Shabana Anjum [4]

Share this Article