International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 111

Research Paper | Chemistry | India | Volume 4 Issue 4, April 2015


Microwave-Assisted Synthesis and Biological Activities of Some Chromene Derivatives

Vrushali Patil, Ashish Asrondkar, Anil Bobade, Abhay Chowdhary


Abstract: A series of 4H-chromene derivatives were synthesized under microwave irradiation, a comparative study was done depending upon yield and time. The present study reveals the synthesis of chromene derivative in which pyrazine-2-ol was reacted with chloroethylacetate in presence of K2CO3 to form an intermediate which was further treated with hydrazine hydrate to form hydrazino derivative of pyrazine-2-ol and finally the intermediate is condensed by substituted chromene derivatives to form final compound conventionally as well as by using microwave irradiation technique. The synthesized compounds were then characterized by using FT-IR, 1H-NMR and Mass spectrophotometer. All the compounds were screened for their anti-microbial activity, anti-oxidant and anti-inflammatory activity. It was found that the derivatives showed moderate activity as compared to standard.


Keywords: Microwave assisted synthesis, Chromene, Anti-bacterial activity, Anti-inflammatory activity


Edition: Volume 4 Issue 4, April 2015,


Pages: 1688 - 1690


How to Cite this Article?

Vrushali Patil, Ashish Asrondkar, Anil Bobade, Abhay Chowdhary, "Microwave-Assisted Synthesis and Biological Activities of Some Chromene Derivatives", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SUB153388, Volume 4 Issue 4, April 2015, 1688 - 1690

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Microwave assisted synthesis'

Downloads: 1

Research Paper, Chemistry, India, Volume 10 Issue 9, September 2021

Pages: 126 - 128

Microwave Assisted Synthesis and Thermal Behavior Study of a Compound Containing 1, 3, 4 - Oxadiazole Rings

Varsha V. Thorat

Share this Article

Downloads: 111

Research Paper, Chemistry, India, Volume 7 Issue 4, April 2018

Pages: 1186 - 1190

Complex Catalyzed Microwave Assisted Green Synthesis of Guargum-g-P (MMA-co-AM) / MMT Nanocomposite Superabsorbent

Pramilarani Behera, Prafulla K Sahoo

Share this Article

Similar Articles with Keyword 'Antibacterial activity'

Downloads: 44

Research Paper, Chemistry, India, Volume 10 Issue 1, January 2021

Pages: 1474 - 1479

Synthesis, Spectral Characterization and Antibacterial Activity of Metal Complexes of 2-Methoxy benzaldehyde isonicotinoylhydrazone

E. Lakshmi, T. Krishna, A. Suseelamma, P. Raveendra Reddy

Share this Article

Downloads: 97

Research Paper, Chemistry, India, Volume 9 Issue 3, March 2020

Pages: 1472 - 1474

Synthesis and Antibacterial Activity of Complexes of 2, 2-Dipyridyldisulphide with ND(III) and TB(III) Metals

Kavita L. Kendre, Girish Pande

Share this Article

Similar Articles with Keyword 'Microwave'

Downloads: 0

Research Paper, Chemistry, India, Volume 10 Issue 7, July 2021

Pages: 1362 - 1364

Phototungstic Acid Catalyzed Synthesis of Benzo (h) Chromen-2-one3-methyl Carboxylate and Study its Anti-Inflammatory Property

Anna R. Anthony

Share this Article

Downloads: 1

Research Paper, Chemistry, India, Volume 10 Issue 9, September 2021

Pages: 126 - 128

Microwave Assisted Synthesis and Thermal Behavior Study of a Compound Containing 1, 3, 4 - Oxadiazole Rings

Varsha V. Thorat

Share this Article

Similar Articles with Keyword 'assisted'

Downloads: 1

Research Paper, Chemistry, India, Volume 10 Issue 9, September 2021

Pages: 126 - 128

Microwave Assisted Synthesis and Thermal Behavior Study of a Compound Containing 1, 3, 4 - Oxadiazole Rings

Varsha V. Thorat

Share this Article

Downloads: 111

Research Paper, Chemistry, India, Volume 7 Issue 4, April 2018

Pages: 1186 - 1190

Complex Catalyzed Microwave Assisted Green Synthesis of Guargum-g-P (MMA-co-AM) / MMT Nanocomposite Superabsorbent

Pramilarani Behera, Prafulla K Sahoo

Share this Article

Similar Articles with Keyword 'synthesis'

Downloads: 124

Research Paper, Chemistry, United Kingdom, Volume 4 Issue 1, January 2015

Pages: 1527 - 1529

Antibacterial Studies of Leucine Complexes of Fe (III) and Cu (II)

K. Asemave, B. A. Anhwange, T. J. Anom

Share this Article

Downloads: 0

Research Paper, Chemistry, India, Volume 10 Issue 7, July 2021

Pages: 1362 - 1364

Phototungstic Acid Catalyzed Synthesis of Benzo (h) Chromen-2-one3-methyl Carboxylate and Study its Anti-Inflammatory Property

Anna R. Anthony

Share this Article
Top