International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 126

Survey Paper | Medicine Science | Macedonia | Volume 4 Issue 1, January 2015


The Prevalence of Δ508 in Cystic Fibrosis Patients with Low Bone Mineral Density in Republic of Macedonia

Tatjana Jakovska, Tatjana Zorcec


Abstract: Introduction Reduced bone mass density (BMD) is frequent in patients with cystic fibrosis (CF). Pathogenesis of CF bone disease is multifactorial. Many studies suggest that there is genetic component, independent of the disease severity and nutritional deficits. Aim To determine the prevalence and identify determinants of reduced BMD in CF patients. Material and methods The study included 80 CF patients (range 5-36y. ). BMD was measured via dual-energy x-ray absorptiometry (DXA) scan. Vitamin D level was assessed by plasma 25OHD levels (


Keywords: bone mineral density, cystic fibrosis, F508 genotype, vitamin D deficiency


Edition: Volume 4 Issue 1, January 2015,


Pages: 771 - 774


How to Cite this Article?

Tatjana Jakovska, Tatjana Zorcec, "The Prevalence of Δ508 in Cystic Fibrosis Patients with Low Bone Mineral Density in Republic of Macedonia", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SUB15303, Volume 4 Issue 1, January 2015, 771 - 774

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