International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064

Downloads: 123

Research Paper | Biochemistry Science | India | Volume 4 Issue 3, March 2015

Antioxidant Reviving Role of Mint-Tea on Placenta During Gestational Diabetes Mellitus

Padmini Ekambaram [5] | Kalyani Gopal | Christina Joseph Mary Susai

Abstract: In the global scenario, about 1-14 % of pregnancies are associated with increased perinatal morbidity, mortality due to increased risk of pregnancy-induced disorders. Gestational diabetes mellitus (GDM) is one of the severe and serious condition that occur due to high blood glucose levels during pregnancy, which leads to variety of structural and functional changes in placenta. Placental injury due to free radical induced oxidative stress (OS) plays a crucial role in the pathogenesis of complications during diabetic gestation. To ameliorate OS induction during diabetic pregnancy, herbs containing potential antioxidant constituents are required. Mint (Mentha spicata) and Tea (Camellia sinensis) are the renowned aromatic herbs rich in effective antioxidants. Hence the present study aims to monitor the possible beneficial effect of mint-tea on OS markers such as LPO, NO2-, HNE, ADMA, antioxidants such as SOD, TAC, GRR along with the analysis of HSP70 expression. Oxidant-antioxidant imbalance along with increased expression of HSP70 was observed in the GDM placental homogenate without mint-tea incubation. Mint-tea incubation diminished the oxidants and increased the antioxidants which subsequently results in decreased HSP70 expression in GDM placental homogenate. The results revealed that mint-tea extract renders more cell protection and implying their effect in modulating GDM associated stress is more pronounced in combined form than their sole use. Hence the mint-tea extracts can be employed as an alternative herbal remedy to prevent the OS mediated complications during GDM.

Keywords: Gestational diabetes mellitus GDM, Mint, Tea, Heat shock protein 70 HSP70 Oxidative stress OS

Edition: Volume 4 Issue 3, March 2015,

Pages: 501 - 507

How to Cite this Article?

Padmini Ekambaram, Kalyani Gopal, Christina Joseph Mary Susai, "Antioxidant Reviving Role of Mint-Tea on Placenta During Gestational Diabetes Mellitus", International Journal of Science and Research (IJSR), Volume 4 Issue 3, March 2015, pp. 501-507,

How to Share this Article?

Enter Your Email Address

Similar Articles with Keyword 'Tea'

Downloads: 43

Research Paper, Biochemistry Science, Kenya, Volume 5 Issue 7, July 2016

Pages: 556 - 559

A Functional Comparison of the Archaeon Tricorn Protease and Selected Serine Proteases from Trypanosoma brucei brucei

Ng'ong'a F.A | Wamunyokoli F | Nyanjom S. R. G

Share this Article

Downloads: 98

Research Paper, Biochemistry Science, Ivory Coast, Volume 4 Issue 9, September 2015

Pages: 1727 - 1736

Optimization of Post-Harvest Maize Storage using Biopesticides in Granaries in Rural Environment of C?te d?Ivoire

L. Niamketchi | H. G. Biego [2] | O. Chatigre [2] | D. Aman | E. Koffi [2] | A. Adima [2]

Share this Article