Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
www.ijsr.net | Most Trusted Research Journal Since Year 2012

ISSN: 2319-7064



Research Paper | Pediatrics | India | Volume 4 Issue 2, February 2015

Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital

Munagala Venkata Krishna D.N.B, P. Muni Lakshmi M.D

Neonatal sepsis is the commonest causes of neonatal mortality in the developing world. Aims & Objective To determine the bacteriological profile of neonatal septicaemia, their antibacterial susceptibility pattern. MATERIALS &METHODSA total of 486 neonates (< 1week of age) suspected septicemia admitted in NICU enrolled over a period of 10 months.1-2 ml of blood collected in aseptic conditions inoculated immediately into 5 ml of brain heart infusion broth with 0.025 % Sodium polyanethol sulfonate as anticoagulant. The broths were subcultured after overnight incubation on chocolate agar, MacConkey agar and 5 %sheep blood agar. organisms isolated kept for biochemical tests for confirmation then checked for Antibiotic sensitivity by Kirby-Bauer disk diffusion method. ResultsOut of 486 cases studied, growth of bacteria was obtained in 44.03 % blood samples.The most frequent offender was Klebsiella spp 25.7 %. followed by E. coli 22.4 % Enterobacter spp.18.6 %, CONS 14.9 %, S. aureus 11.2 % and other less frequent isolates. Study of maternal risk factors revealed 30.8 % of mothers had preterm labor, 22.4 % had PROM and 1.4 % had intra partum fever. The most frequent neonatal risk factor was low birth weight affecting 64 % of the neonates The antimicrobial susceptibility testing revealed that resistance to penicillin was frequent in S. aureus 95.8 % and CONS 87.5 % than in Enterococcus spp 33.3 %. Resistance to amikacin was relatively uncommon in the former two isolates.None of the gram positive isolates were resistant to the glycopeptides - vancomycin and teicoplanin. Most of the gram negative isolates of Enterobacteriaceae family were resistant to ampicillin and amoxycillin

Keywords: Septicemia, Kirby-Bauer disk diffusion, Antimicrobial resistance, Enterobacteriaceae, LBW

Edition: Volume 4 Issue 2, February 2015

Pages: 1300 - 1303

Share this Article

How to Cite this Article?

Munagala Venkata Krishna D.N.B, P. Muni Lakshmi M.D, "Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SUB151401, Volume 4 Issue 2, February 2015, 1300 - 1303

37 PDF Views | 38 PDF Downloads

Download Article PDF



Similar Articles with Keyword 'Septicemia'

Research Paper, Pediatrics, India, Volume 4 Issue 2, February 2015

Pages: 1300 - 1303

Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital

Munagala Venkata Krishna D.N.B, P. Muni Lakshmi M.D

Share this Article

Research Paper, Pediatrics, India, Volume 8 Issue 11, November 2019

Pages: 725 - 727

Analysis of Mortality in PICU of a Tertiary Care Teaching Hospital

Dr. Ruchi Jha, Dr. Neelam Verma

Share this Article

Similar Articles with Keyword 'LBW'

Research Paper, Pediatrics, India, Volume 4 Issue 2, February 2015

Pages: 1300 - 1303

Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital

Munagala Venkata Krishna D.N.B, P. Muni Lakshmi M.D

Share this Article

Research Paper, Pediatrics, Saudi Arabia, Volume 5 Issue 5, May 2016

Pages: 1111 - 1116

Risk Factors for Low Birth Weight Babies in Hail Region KSA

Rania Abdeen, Aljohrah Albaker, Amal Al-Buqaisi, Hala Alassaf, Latifah Alateeq, Wasmiah Alshammri

Share this Article

Comparative Studies, Pediatrics, India, Volume 4 Issue 12, December 2015

Pages: 675 - 676

Screening for Retinopathy of Prematurity

Dr. Sonu Akhani, Dr. Sucheta Munshi, Dr. K. M. Mehariya

Share this Article

Research Paper, Pediatrics, India, Volume 8 Issue 6, June 2019

Pages: 1879 - 1881

Morbidity among the Referral Babies to Higher Centre from SNCU of Government Tertiary Care Maternity Hospital

Dr. N. Manjuleswari, Dr. Anita Sethi

Share this Article

Research Paper, Pediatrics, India, Volume 4 Issue 7, July 2015

Pages: 752 - 758

Electrolyte Changes Following Phototherapy in Neonatal Hyperbilirubinemia

Dr. A. Thirupathi Reddy, Dr. K. Vani Bai, Dr. S. Uday Shankar

Share this Article
Top