International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Since Year 2012 | Open Access | Double Blind Reviewed

ISSN: 2319-7064

Downloads: 114

Research Paper | Pediatrics | India | Volume 4 Issue 2, February 2015

Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital

Munagala Venkata Krishna D.N.B | P. Muni Lakshmi M.D

Abstract: Neonatal sepsis is the commonest causes of neonatal mortality in the developing world. Aims & Objective To determine the bacteriological profile of neonatal septicaemia, their antibacterial susceptibility pattern. MATERIALS & METHODSA total of 486 neonates (< 1week of age) suspected septicemia admitted in NICU enrolled over a period of 10 months.1-2 ml of blood collected in aseptic conditions inoculated immediately into 5 ml of brain heart infusion broth with 0.025 % Sodium polyanethol sulfonate as anticoagulant. The broths were subcultured after overnight incubation on chocolate agar, MacConkey agar and 5 %sheep blood agar. organisms isolated kept for biochemical tests for confirmation then checked for Antibiotic sensitivity by Kirby-Bauer disk diffusion method. ResultsOut of 486 cases studied, growth of bacteria was obtained in 44.03 % blood samples. The most frequent offender was Klebsiella spp 25.7 %. followed by E. coli 22.4 % Enterobacter spp.18.6 %, CONS 14.9 %, S. aureus 11.2 % and other less frequent isolates. Study of maternal risk factors revealed 30.8 % of mothers had preterm labor, 22.4 % had PROM and 1.4 % had intra partum fever. The most frequent neonatal risk factor was low birth weight affecting 64 % of the neonates The antimicrobial susceptibility testing revealed that resistance to penicillin was frequent in S. aureus 95.8 % and CONS 87.5 % than in Enterococcus spp 33.3 %. Resistance to amikacin was relatively uncommon in the former two isolates. None of the gram positive isolates were resistant to the glycopeptides - vancomycin and teicoplanin. Most of the gram negative isolates of Enterobacteriaceae family were resistant to ampicillin and amoxycillin

Keywords: Septicemia, Kirby-Bauer disk diffusion, Antimicrobial resistance, Enterobacteriaceae, LBW

Edition: Volume 4 Issue 2, February 2015,

Pages: 1300 - 1303

How to Cite this Article?

Munagala Venkata Krishna D.N.B, P. Muni Lakshmi M.D, "Bacteriology of Early Onset Neonatal Septicaemia in a Tertiary Care Hospital", International Journal of Science and Research (IJSR), Volume 4 Issue 2, February 2015, pp. 1300-1303,

How to Share this Article?

Similar Articles with Keyword 'LBW'

Downloads: 92

Research Paper, Pediatrics, India, Volume 9 Issue 10, October 2020

Pages: 329 - 334

Effectiveness of Structured Teaching Programme on Knowledge and Practice of Mothers regarding Feeding Practice of Low Birth Weight Newborns in NICU, KGMU

Payal Saha | Rina Kumari | S. N. Singh [2] | Anugrah Charan

Share this Article

Downloads: 106

Research Paper, Pediatrics, Saudi Arabia, Volume 5 Issue 5, May 2016

Pages: 1111 - 1116

Risk Factors for Low Birth Weight Babies in Hail Region KSA

Rania Abdeen | Aljohrah Albaker | Amal Al-Buqaisi | Hala Alassaf | Latifah Alateeq | Wasmiah Alshammri

Share this Article