International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


Downloads: 115 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Pharmacology Science | India | Volume 3 Issue 12, December 2014


Phytochemical Analysis and Antibacterial Activity of Mirabilis jalapa Flower against Gastro Intestinal Pathogens

Sumithra P, Varalakshmi S, Devasena K


Abstract: Mirabilis jalapa Linn. is widely used as a traditional medicine in many parts of the world for the treatment of various diseases viz. viral inhibitory activity, anti tumour activity. It is claimed in traditional medicine as the flower of the plant is used in the treatment of dysentery, diarrhea, muscular pain and abdominal colic. In the present study was attempted to reveal the qualitative phytochemical analysis of dried flower powder extracted in various solvents like aqueous, ethanol, methanol, chloroform and petroleum ether and their antibacterial activity against the gastrointestinal infections causing pathogens like Escherichia coli, Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeroginosa, Klebsiella pneumoniae, Bacillus cereus, Lactobacillus acidophilus, Enterococcus faecalis, Salmonella typhi and Shigella dysenteriae. TLC was carried out in all the extractions and HPLC and FT-IR were used as confirmatory test to study the nature of secondary metabolites. The antibacterial activity of the extracts of Mirabilis jalapa was examined by Disc diffusion method. Aqueous, chloroform and petroleum ether extracts displayed the minimal inhibition while all the ethanolic and methanolic extracts showed good antibacterial activity against the selected pathogens. The bacterial growth inhibition was calculated with reference to the standard.


Keywords: Disc diffusion method, Antibacterial activity, Phytochemicals


Edition: Volume 3 Issue 12, December 2014,


Pages: 1167 - 1170


How to Cite this Article?

Sumithra P, Varalakshmi S, Devasena K, "Phytochemical Analysis and Antibacterial Activity of Mirabilis jalapa Flower against Gastro Intestinal Pathogens", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SUB14548, Volume 3 Issue 12, December 2014, 1167 - 1170

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Phytochemicals'

Downloads: 114

Research Paper, Pharmacology Science, India, Volume 4 Issue 1, January 2015

Pages: 2502 - 2505

Phytochemical Content of Leaf and In Vitro Established Callus Culture of Pisonia alba Span

B. Saritha, Dr. S. Karpagam

Share this Article

Downloads: 119

Research Paper, Pharmacology Science, India, Volume 6 Issue 1, January 2017

Pages: 1836 - 1839

Phytochemical Screening of Methanolic, Pet Ether and Ethyl Acetate Extracts of Helicteres isora Linn

Sunny Sharma, Seema Bhargava, Kalu Singh Chundawat

Share this Article

Similar Articles with Keyword 'Disc'

Downloads: 103

Research Paper, Pharmacology Science, India, Volume 4 Issue 6, June 2015

Pages: 1224 - 1227

Antibacterial Spectrum and Activity Guided Evaluation of Bark of Sonneratia Alba

Mitter C. S.

Share this Article

Downloads: 104

Research Paper, Pharmacology Science, India, Volume 8 Issue 12, December 2019

Pages: 1481 - 1485

Evaluation of Anti Inflammatory Activity of Benazepril in Albino Rats

Meenambal.S, Israel Raja Johnley.I

Share this Article

Similar Articles with Keyword 'diffusion'

Downloads: 103

Research Paper, Pharmacology Science, India, Volume 4 Issue 6, June 2015

Pages: 1224 - 1227

Antibacterial Spectrum and Activity Guided Evaluation of Bark of Sonneratia Alba

Mitter C. S.

Share this Article

Downloads: 104

Survey Paper, Pharmacology Science, Indonesia, Volume 4 Issue 6, June 2015

Pages: 2814 - 2817

NaF Patch Formulation and Transport Test to Determine Fluoride Diffusion via Mouse Skin as Membrane (Transdermal in Vitro Test)

Diyah Fatmasari, Iwan Dwi Prahasto, Widjijono

Share this Article

Similar Articles with Keyword 'method'

Downloads: 124

Research Paper, Pharmacology Science, India, Volume 5 Issue 12, December 2016

Pages: 1400 - 1405

Anticancer Property of Simple Ascidian Phallusia Nigra Savigny, 1816 against MDA-MB-231 Cells

M. Paripooranaselvi, V. K. Meenakshi

Share this Article

Downloads: 53

Case Studies, Pharmacology Science, Argentina, Volume 10 Issue 1, January 2021

Pages: 835 - 839

Meropenem and Valproic Acid Interaction: A Systematic Review of Case Reports and Case Series

Mar?a Graciela Lopez Ordieres, Camila Monte Final, Micaela Ventura, Mar?a S. Viola

Share this Article

Similar Articles with Keyword 'Antibacterial'

Downloads: 103

Research Paper, Pharmacology Science, India, Volume 4 Issue 6, June 2015

Pages: 1224 - 1227

Antibacterial Spectrum and Activity Guided Evaluation of Bark of Sonneratia Alba

Mitter C. S.

Share this Article

Downloads: 124

Research Paper, Pharmacology Science, India, Volume 5 Issue 5, May 2016

Pages: 891 - 894

Green Synthesized Gold Nanoparticle from Kigelia Africana Enhanced the Antibacterial and Antioxidant Activities: An In Vitro Approach

Gunasekaran Vetrichelvi, Kannan Elangovan, S. Niranjali Devaraj

Share this Article

Similar Articles with Keyword 'activity'

Downloads: 124

Research Paper, Pharmacology Science, India, Volume 5 Issue 12, December 2016

Pages: 1400 - 1405

Anticancer Property of Simple Ascidian Phallusia Nigra Savigny, 1816 against MDA-MB-231 Cells

M. Paripooranaselvi, V. K. Meenakshi

Share this Article

Downloads: 57

Research Paper, Pharmacology Science, Ivory Coast, Volume 7 Issue 12, December 2018

Pages: 1172 - 11174

In Vivo Antitussive Activity of Chrysophyllum welwitschii against Ammonia Liquor-Induced Cough in Rats

Agnero S. M.; Pakora G. A.; Yeo Dodehe; N'Guessan J. D.; Djaman A. J.

Share this Article
Top