International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Open Access | Double Blind Reviewed

ISSN: 2319-7064

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Research Paper | Pediatrics | India | Volume 11 Issue 9, September 2022

Endocrinopathies in Thalassemia with Special Reference to Anthropometry

Dr. Priyanka Makwana | Dr. Jatin Jadav

Abstract: Background: Despite intensive iron chelation therapy, growth retardation, hypo gonadotropic hypogonadism, diabetes mellitus, hypothyroidism, hypoparathyroidism, osteopenia and osteoporosis represent the common endocrinopathies in pediatric thalassemia patients. Purpose: To study profile of blood transfusion, chelation therapy and complications in thalassemia children, to study anthropometric measurements, to study the incidence of and growth retardation & endocrine complications in thalassemia patients. Methods: This is observational -prospective study is carried out among children in thalassemia clinic. The detailed history regarding blood transfusion and use of iron chelator taken and various anthropometric measurements recorded. Blood and radio-graphical investigations are done at blood transfusion date or on follow up. Results: Mean duration of blood transfusion was less than 2 week in 31.1%, between 2-4 week in 46.7% and more than 4 week in 22.2%. In present study, height less than 3rd percentile observed in 53.6% male and 64.7% female and between 3rd -50th percentile in 37.1% male and 23.4% female. Weight less than 3rd percentile seen in 32.2% male and 29.4% female while 3rd -50th percentile was observed in 42.8% male and 47% female. Conclusion: Growth retardation was observed in 29.6% of children in present study. Juvenile Diabetes & Hypothyroidism was seen in 2.2% & 1.5% respectively.

Keywords: endocrine, thalassemia, anthropometry, growth retardation, children

Edition: Volume 11 Issue 9, September 2022,

Pages: 400 - 406

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How to Cite this Article?

Dr. Priyanka Makwana, Dr. Jatin Jadav, "Endocrinopathies in Thalassemia with Special Reference to Anthropometry", International Journal of Science and Research (IJSR), Volume 11 Issue 9, September 2022, pp. 400-406,

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