International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




Downloads: 2 | Views: 17

Review Papers | Pharmaceutical Science | Indonesia | Volume 11 Issue 3, March 2022


PfSPZ Malaria Vaccine

Dwi Ayu Fani Novitasari


Abstract: Malaria is a disease caused by parasites. As we know that parasites have 3 life cycles while it?s on the human host: pre-erythrocytes phase, blood-stage phase, and transmission-blocking phase. As for now, the medicine for malaria disease is artemisin combination therapy which is going to be resistant, so people try to develop a vaccine for malaria to meet the goal of malaria eradication. One of the vaccines developed is RTS,S/AS01. RTS,S/AS01 is pre-erythrocytic vaccine that confers efficacy against controlled human malaria infection in about 22% in healthy malaria 5 months after vaccination. In clinical trial phase 3, RTS,S/AS01 was 26% in young infants and 36% in children (Ishizuka et al., 2016). Eradication of malaria needs vaccine protection of more than 80% and has protective efficacy for more than 6 months. Therefore, the development of a malaria vaccine is still needed. Another malaria vaccine is PfSPZ. PfSPZ is pre-erythrocytic stage vaccine similar to RTS,S/AS01. It is whole attenuated sporozoite Plasmodium falciparum.


Keywords: vaccine, malaria, PfSPZ


Edition: Volume 11 Issue 3, March 2022,


Pages: 76 - 77


How to Download this Article?

Type Your Email Address below to Download the Article PDF


How to Cite this Article?

Dwi Ayu Fani Novitasari, "PfSPZ Malaria Vaccine", International Journal of Science and Research (IJSR), Volume 11 Issue 3, March 2022, pp. 76-77, https://www.ijsr.net/get_abstract.php?paper_id=SR22315171651



Similar Articles with Keyword 'vaccine'

Downloads: 124 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Pharmaceutical Science, India, Volume 9 Issue 2, February 2020

Pages: 1858 - 1860

Ebola

Anshupa Patel Gupta [2] | Himani Tambde [3]

Share this Article

Downloads: 3 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Review Papers, Pharmaceutical Science, India, Volume 10 Issue 6, June 2021

Pages: 1431 - 1435

A Concise Review on Liposomes: A Novel Approach

Vivek Kumar Mishra [2] | Pallavi Tiwari [7]

Share this Article



Top