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Research Paper | Anaesthesiology | India | Volume 11 Issue 1, January 2022

Recovery Profile Following General Anaesthesia with Isoflurane in Relation to Body Mass Index and Duration of Anaesthesia in Patients Undergoing Thyroidectomy

Vidya .S | Baburaj .C ^[2] | Anup .P

Abstract: Background: Increased BMI may increase the body?s capacity to store potent inhaled anaesthetics, more so with more soluble agents. This study is intended to know whether increased BMI is associated with delay in recovery of verbal response, motor power and cognition after anaesthesia with Isoflurane. Objectives: Primary objective: To study recovery profile following general anaesthesia with isoflurane in patients undergoing total thyroidectomy. Secondary objectives: To study the effect of body mass index and to study the effect of duration of anaesthesia on recovery following anaesthesia with isoflurane. Materials & Method: This hospital based cross sectional study conducted at Dept of Anaesthesiology, Govt medical college, Trivandrum included a total of 96 patients undergoing total thyroidectomy under GA. Outcome variables measured are recovery time in terms of response to verbal commands, adequate motor power and cognition following anaesthesia with isoflurane. RESULTS: The correlation coefficient between BMI & recovery times are 0.51, 0.47& 0.45 respectively indicating moderate correlation. P value above is <0.001 suggesting that the correlation is highly significant. The correlation coefficient between DOA & recovery times are 0.01,0.033& 0.0 respectively indicating very weak correlation. P value above is > 0.05 suggesting that the correlation is not significant. Conclusion: From the present study it can be concluded that there is statistically significant (moderate) correlation between recovery times and BMI. Recovery times in patients with BMI>23Kg/m2 are prolonged as compared to that of with patients BMI<23 Kg/m2. There was no statistically significant correlation between DOA and recovery times.

Keywords: Inhaled anesthetics, Isoflurane, Body Mass Index, Recovery times, Duration of anesthesia

Edition: Volume 11 Issue 1, January 2022,

Pages: 1027 - 1045

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