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Research Paper | Medicine | India | Volume 11 Issue 10, October 2022

Diastolic Dysfunction in Type 2 Diabetes and its Correlation with Retinopathy and Nephropathy

Devarshi Patel | Nidhi Mehta | Ravi Patel | Ronak Bhanat | Asha Shah | Shaila Shah | Vipul Prajapati | Hemaxi Desai

Abstract: Introduction: The prevalence of diabetes mellitus is on rising trend in developing countries like India. This burden of diabetes brings it with the potential for a catastrophic increase in the prevalence of renal, ophthalmic and cardiovascular complications. Objectives: This study is to assess the diastolic dysfunction in type 2 diabetic patients using Doppler 2D echocardiography and also to find out the correlation between diastolic dysfunction and microvascular complications (nephropathy and retinopathy). Methods: A cross sectional observational study was conducted in GCS HOSPITAL, Ahmedabad over a period of 6 months from July 2021 to December 2021 in type 2 diabetes mellitus patients. A total of 50 cases were observed in this study on both indoor and outdoor basis. All patients were taken for 2D echocardiography to assess diastolic dysfunction on the basis of E/A and E/E' ratio. Fundus examination and urine microalbumin has been done to detect retinopathy and nephropathy respectively. Results: There was a significant correlation between age, duration of type 2 diabetes mellitus, diastolic dysfunction, diabetic nephropathy and retinopathy. In this study, risk of diastolic dysfunction increases with age and duration of diabetes mellitus. Incidence of retinopathy (p value 0.0004) and nephropathy (p value-0.0002) are more in patients with diastolic dysfunction compared to patients not having diastolic dysfunction. Conclusion: Results of the present study reveals that there is significant evidence to support the conclusion that diabetic individuals with diastolic dysfunction having higher risk of developing microvascular complications such as nephropathy and retinopathy.

Keywords: Diabetes Mellitus, Diastolic Dysfunction, Nephropathy, Retinopathy

Edition: Volume 11 Issue 10, October 2022,

Pages: 653 - 659

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