International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064


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Case Studies | Orthopedic | Indonesia | Volume 10 Issue 9, September 2021


β - Thalassemia Intermedia with Severe Bone Abnormality

I Ketut Suyasa, I Gusti Ngurah Wien Aryana, Hendra Aryudi Hamzah


Abstract: Introduction: β - thalassemia (βth) is a congenital hematologic disorder that affects the production of β - globin chains, resulting in impaired haemoglobin function. βth is classified into β - Thalassemia minor, β - Thalassemia intermedia (βti), and β - Thalassemia major. Bone abnormalities are common including osteoporosis and fracture in βti patients. This case study aims to highlightthe features of bone abnormalities in β - thalassemia intermedia patients. Case Description: A 25 - year - old woman with β - Thalassemia intermedia (βti) presented to our clinic with pain on her right knee and inability to bear her weight, after stumbling and falling during her way to the bathroom. Patient had previous history of trauma affecting her left leg. On radiographic examination, we found a right distal femoral fracture and a left subtrochanteric fracture. The patient was treated by packed red cell transfusion, internal fixation, and bisphosphonate. After two months of evaluation, the fractures had started to unite and the patient had improved her range of motion of her both leg. Bone abnormalities are common in βti patients including pathologic fracture in long bones. These patients should be treated comprehensively in order to improve bone density andlower the risk of fractures.


Keywords: Case report, Pathologic fracture, Bone abnormalities, β - Thalassemia


Edition: Volume 10 Issue 9, September 2021,


Pages: 1183 - 1186


How to Cite this Article?

I Ketut Suyasa, I Gusti Ngurah Wien Aryana, Hendra Aryudi Hamzah, "β - Thalassemia Intermedia with Severe Bone Abnormality", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SR21924144213, Volume 10 Issue 9, September 2021, 1183 - 1186

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