International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064




Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Case Studies | Pathology | Indonesia | Volume 10 Issue 9, September 2021


Therapy - Related Myeloid Neoplasms: A Case Report

Herman Saputra, Nicolas Xavier Ongko


Abstract: Introduction: Therapy - related myeloid neoplasms is a neoplasm that occur as a late complication of cytotoxic chemotherapy and/ or radiation therapy administered for a prior neoplastic or non - neoplastic disease. This neoplasm account for 10 - 20% of all cases of myeloid neoplasm. This paper reports a case of a 61 - year - old male with complaints of saddle - back fever for 1 month. The patient previously had a parotid gland malignancy in 2015 and had been treated with radiation therapy for 25 times. Case description: Microscopic examination shows a trephine biopsy consist of trabecular bone with a marrow spaces. Bone marrow shows a hypercellular appearance. Focus of ALIP (abnormal location of immature precursor) can be observed. The hemopoietic cells consist of myeloid, erythroid and megakaryocytic lineage. The erythroid lineage consists of normoblast. The myeloid lineage shows maturation with focus of increased blast count < 20% (monoblast, myeloblast and promonocyte). Megakariocyte shows prominent hypolobated - micromegakaryocytic features (suggest a dysmegakariopoiesis features). Conclusions: Based on clinical data, laboratory and histopathological examination, the patient was diagnosed with therapy - related myeloid neoplasms.


Keywords: Therapy - related myeloid neoplasms, blast count, dysmegakariopoiesis


Edition: Volume 10 Issue 9, September 2021,


Pages: 157 - 160


How to Cite this Article?

Herman Saputra, Nicolas Xavier Ongko, "Therapy - Related Myeloid Neoplasms: A Case Report", International Journal of Science and Research (IJSR), https://www.ijsr.net/get_abstract.php?paper_id=SR21904121057, Volume 10 Issue 9, September 2021, 157 - 160

How to Share this Article?

Enter Your Email Address


Similar Articles with Keyword 'Therapy'

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Case Studies, Pathology, India, Volume 11 Issue 1, January 2022

Pages: 553 - 557

Recurrent Dermatofibrosarcoma Protuberans - An Institutional Case Series over a Span of 7 Years

Fathima Seles .M

Share this Article

Downloads: 3

Case Studies, Pathology, India, Volume 10 Issue 10, October 2021

Pages: 119 - 123

Pancreatic Tuberculosis or Tumor: A Diagnostic Dilemma

Rohit Sharma, Kavya Goel, Sufian Zaheer, Ashwin Barsagade

Share this Article
Top