Abstract: Therapy - Related Myeloid Neoplasms: A Case Report
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Open Access | Fully Refereed | Peer Reviewed

ISSN: 2319-7064

Downloads: 1 | Monthly Hits: ⮙1

Case Studies | Pathology | Indonesia | Volume 10 Issue 9, September 2021

Therapy - Related Myeloid Neoplasms: A Case Report

Herman Saputra, Nicolas Xavier Ongko

Introduction: Therapy - related myeloid neoplasms is a neoplasm that occur as a late complication of cytotoxic chemotherapy and/ or radiation therapy administered for a prior neoplastic or non - neoplastic disease. This neoplasm account for 10 - 20% of all cases of myeloid neoplasm. This paper reports a case of a 61 - year - old male with complaints of saddle - back fever for 1 month. The patient previously had a parotid gland malignancy in 2015 and had been treated with radiation therapy for 25 times. Case description: Microscopic examination shows a trephine biopsy consist of trabecular bone with a marrow spaces. Bone marrow shows a hypercellular appearance. Focus of ALIP (abnormal location of immature precursor) can be observed. The hemopoietic cells consist of myeloid, erythroid and megakaryocytic lineage. The erythroid lineage consists of normoblast. The myeloid lineage shows maturation with focus of increased blast count < 20% (monoblast, myeloblast and promonocyte). Megakariocyte shows prominent hypolobated - micromegakaryocytic features (suggest a dysmegakariopoiesis features). Conclusions: Based on clinical data, laboratory and histopathological examination, the patient was diagnosed with therapy - related myeloid neoplasms.

Keywords: Therapy - related myeloid neoplasms, blast count, dysmegakariopoiesis

Edition: Volume 10 Issue 9, September 2021

Pages: 157 - 160

Share this Article

How to Cite this Article?

Herman Saputra, Nicolas Xavier Ongko, "Therapy - Related Myeloid Neoplasms: A Case Report", International Journal of Science and Research (IJSR), https://www.ijsr.net/search_index_results_paperid.php?id=SR21904121057, Volume 10 Issue 9, September 2021, 157 - 160

Enter Your Email Address

Similar Articles with Keyword 'Therapy'

Downloads: 42

Research Paper, Pathology, Libya, Volume 10 Issue 3, March 2021

Pages: 865 - 871

Correlation of Nuclear Factor Erythroid 2-Related Factor (NRF2) Expression Level with the Efficacy of Brusatol in Urothelial Cell Carcinoma Cell Lines

Khaled M Ahmed Darraz, Hanan M Garalla

Share this Article

Downloads: 100

Research Paper, Pathology, India, Volume 9 Issue 5, May 2020

Pages: 1526 - 1533

Immunohistochemical Expression in Gliomas - CD117 in a Prognostic and Theranostic Vision

Jayanandhini M, Ramya P, Saraswathi M

Share this Article